Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver
Surgical excision remains the preferred treatment for resectable hepatic metastases of neuroendocrine tumors. In cases of more disseminated hepatic disease, transarterial radioembolization with Yttrium-90- (90Y-) labeled microspheres has been demonstrated as a viable option for symptom and locoregio...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.4061/2011/785315 |
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| _version_ | 1832558191136735232 |
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| author | Martin Vyleta Douglas Coldwell |
| author_facet | Martin Vyleta Douglas Coldwell |
| author_sort | Martin Vyleta |
| collection | DOAJ |
| description | Surgical excision remains the preferred treatment for resectable hepatic metastases of
neuroendocrine tumors. In cases of more disseminated hepatic disease, transarterial
radioembolization with Yttrium-90- (90Y-) labeled microspheres has been demonstrated as a
viable option for symptom and locoregional tumor control. On an outpatient basis,
radioembolization can be utilized from early line to salvage phases, in various combinations with
systemic therapies. Review of available data shows encouraging safety and efficacy profiles for
the intraarterial application of 90Y for the treatment of mNETs of the liver. Symptom control and
decrease in somatostatin analog use can be achieved, as well as prolonged survival. |
| format | Article |
| id | doaj-art-9ef14c3e96814a2a9d7390678e0dff24 |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-9ef14c3e96814a2a9d7390678e0dff242025-02-03T01:32:58ZengWileyInternational Journal of Hepatology2090-34482090-34562011-01-01201110.4061/2011/785315785315Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the LiverMartin Vyleta0Douglas Coldwell1Department of Radiology, University of Louisville School of Medicine, Louisville, KY 40202, USADepartment of Radiology, University of Louisville School of Medicine, Louisville, KY 40202, USASurgical excision remains the preferred treatment for resectable hepatic metastases of neuroendocrine tumors. In cases of more disseminated hepatic disease, transarterial radioembolization with Yttrium-90- (90Y-) labeled microspheres has been demonstrated as a viable option for symptom and locoregional tumor control. On an outpatient basis, radioembolization can be utilized from early line to salvage phases, in various combinations with systemic therapies. Review of available data shows encouraging safety and efficacy profiles for the intraarterial application of 90Y for the treatment of mNETs of the liver. Symptom control and decrease in somatostatin analog use can be achieved, as well as prolonged survival.http://dx.doi.org/10.4061/2011/785315 |
| spellingShingle | Martin Vyleta Douglas Coldwell Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver International Journal of Hepatology |
| title | Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver |
| title_full | Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver |
| title_fullStr | Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver |
| title_full_unstemmed | Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver |
| title_short | Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver |
| title_sort | radioembolization in the treatment of neuroendocrine tumor metastases to the liver |
| url | http://dx.doi.org/10.4061/2011/785315 |
| work_keys_str_mv | AT martinvyleta radioembolizationinthetreatmentofneuroendocrinetumormetastasestotheliver AT douglascoldwell radioembolizationinthetreatmentofneuroendocrinetumormetastasestotheliver |