Radioembolization in the Treatment of Neuroendocrine Tumor Metastases to the Liver
Surgical excision remains the preferred treatment for resectable hepatic metastases of neuroendocrine tumors. In cases of more disseminated hepatic disease, transarterial radioembolization with Yttrium-90- (90Y-) labeled microspheres has been demonstrated as a viable option for symptom and locoregio...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.4061/2011/785315 |
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| Summary: | Surgical excision remains the preferred treatment for resectable hepatic metastases of
neuroendocrine tumors. In cases of more disseminated hepatic disease, transarterial
radioembolization with Yttrium-90- (90Y-) labeled microspheres has been demonstrated as a
viable option for symptom and locoregional tumor control. On an outpatient basis,
radioembolization can be utilized from early line to salvage phases, in various combinations with
systemic therapies. Review of available data shows encouraging safety and efficacy profiles for
the intraarterial application of 90Y for the treatment of mNETs of the liver. Symptom control and
decrease in somatostatin analog use can be achieved, as well as prolonged survival. |
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| ISSN: | 2090-3448 2090-3456 |