Exploration of the potential therapeutic effects and targets of Coriandrum sativum on non-erosive esophagitis based on bioinformatics and molecular dynamics simulation

Exploration of the potential therapeutic effects and targets of Coriandrum sativum on non-erosive esophagitis based on bioinformatics and molecular dynamics simulation

Abstract Gastroesophageal reflux disease (GERD) is one of the most frequently diagnosed gastrointestinal disorders, adversely affecting quality of life. Coriandrum sativum has been shown to effectively promote gastrointestinal motility, alleviate gastric discomfort, and positively impact esophageal...

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Bibliographic Details
Main Authors: Xiaopeng Shen, Bin Li, Yuan Chen, Yixin Wang, Weijun Zhou, Mengyu Deng, Yuling Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Non-erosive reflux disease
Coriandrum sativum
WGCNA
Machine learning
Molecular docking
Molecular dynamics simulations
Online Access:https://doi.org/10.1038/s41598-025-03945-1
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