Left ventricular structure and function in chronic renal disease

Aim. To investigate left ventricular (LV) remodelling variants in patients with chronic renal disease.Material and methods. The study included 150 patients with primary renal parenchymal disease, various stages of chronic kidney failure (CKF), and secondary arterial hypertension (AH). General clinic...

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Main Authors: V. V. Skibitsky, M. M. Dudar, A. K. Arutyunov, A. V. Fendrikova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2009-12-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/1501
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author V. V. Skibitsky
M. M. Dudar
A. K. Arutyunov
A. V. Fendrikova
author_facet V. V. Skibitsky
M. M. Dudar
A. K. Arutyunov
A. V. Fendrikova
author_sort V. V. Skibitsky
collection DOAJ
description Aim. To investigate left ventricular (LV) remodelling variants in patients with chronic renal disease.Material and methods. The study included 150 patients with primary renal parenchymal disease, various stages of chronic kidney failure (CKF), and secondary arterial hypertension (AH). General clinical examination, laboratory tests, and renal function assessment were performed. LV remodelling was assessed by echocardiography.Results. LV concentric and eccentric hypertrophy (LVCH and LVEH) were more prevalent in more advanced stages of CKF, and were often combined with rigid and pseudo-normal types of diastolic dysfunction. In patients on hemodialysis, LVEH was associated with restrictive and pseudo-normal types of diastolic dysfunction. In hemodialysis patients, the symptoms of chronic heart failure (CHF) were explained by systolic and diastolic dysfunction, while early CKF stages were associated with diastolic HF only.Conclusion. In chronic renal disease, structural and functional LV changes require active drug therapy, delaying the progression of myocardial remodelling and HF.
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institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 2009-12-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-9ec1a0344dd5449eabfc2680311f503f2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252009-12-018644491219Left ventricular structure and function in chronic renal diseaseV. V. Skibitsky0M. M. Dudar1A. K. Arutyunov2A. V. Fendrikova3Kuban’ State Medical UniversityKuban’ State Medical UniversityKuban’ State Medical UniversityKuban’ State Medical UniversityAim. To investigate left ventricular (LV) remodelling variants in patients with chronic renal disease.Material and methods. The study included 150 patients with primary renal parenchymal disease, various stages of chronic kidney failure (CKF), and secondary arterial hypertension (AH). General clinical examination, laboratory tests, and renal function assessment were performed. LV remodelling was assessed by echocardiography.Results. LV concentric and eccentric hypertrophy (LVCH and LVEH) were more prevalent in more advanced stages of CKF, and were often combined with rigid and pseudo-normal types of diastolic dysfunction. In patients on hemodialysis, LVEH was associated with restrictive and pseudo-normal types of diastolic dysfunction. In hemodialysis patients, the symptoms of chronic heart failure (CHF) were explained by systolic and diastolic dysfunction, while early CKF stages were associated with diastolic HF only.Conclusion. In chronic renal disease, structural and functional LV changes require active drug therapy, delaying the progression of myocardial remodelling and HF.https://cardiovascular.elpub.ru/jour/article/view/1501chronic renal diseaseleft ventricular remodellingdiastolic dysfunctionheart failure
spellingShingle V. V. Skibitsky
M. M. Dudar
A. K. Arutyunov
A. V. Fendrikova
Left ventricular structure and function in chronic renal disease
Кардиоваскулярная терапия и профилактика
chronic renal disease
left ventricular remodelling
diastolic dysfunction
heart failure
title Left ventricular structure and function in chronic renal disease
title_full Left ventricular structure and function in chronic renal disease
title_fullStr Left ventricular structure and function in chronic renal disease
title_full_unstemmed Left ventricular structure and function in chronic renal disease
title_short Left ventricular structure and function in chronic renal disease
title_sort left ventricular structure and function in chronic renal disease
topic chronic renal disease
left ventricular remodelling
diastolic dysfunction
heart failure
url https://cardiovascular.elpub.ru/jour/article/view/1501
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AT mmdudar leftventricularstructureandfunctioninchronicrenaldisease
AT akarutyunov leftventricularstructureandfunctioninchronicrenaldisease
AT avfendrikova leftventricularstructureandfunctioninchronicrenaldisease