Left ventricular structure and function in chronic renal disease
Aim. To investigate left ventricular (LV) remodelling variants in patients with chronic renal disease.Material and methods. The study included 150 patients with primary renal parenchymal disease, various stages of chronic kidney failure (CKF), and secondary arterial hypertension (AH). General clinic...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2009-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1501 |
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| Summary: | Aim. To investigate left ventricular (LV) remodelling variants in patients with chronic renal disease.Material and methods. The study included 150 patients with primary renal parenchymal disease, various stages of chronic kidney failure (CKF), and secondary arterial hypertension (AH). General clinical examination, laboratory tests, and renal function assessment were performed. LV remodelling was assessed by echocardiography.Results. LV concentric and eccentric hypertrophy (LVCH and LVEH) were more prevalent in more advanced stages of CKF, and were often combined with rigid and pseudo-normal types of diastolic dysfunction. In patients on hemodialysis, LVEH was associated with restrictive and pseudo-normal types of diastolic dysfunction. In hemodialysis patients, the symptoms of chronic heart failure (CHF) were explained by systolic and diastolic dysfunction, while early CKF stages were associated with diastolic HF only.Conclusion. In chronic renal disease, structural and functional LV changes require active drug therapy, delaying the progression of myocardial remodelling and HF. |
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| ISSN: | 1728-8800 2619-0125 |