scRNA-seq revealed transcriptional signatures of human umbilical cord primitive stem cells and their germ lineage origin regulated by imprinted genes

scRNA-seq revealed transcriptional signatures of human umbilical cord primitive stem cells and their germ lineage origin regulated by imprinted genes

Abstract A population of CD133+lin-CD45- and CD34+lin-CD45- very small embryonic-like stem cells (VSELs) has been identified in postnatal human tissues, including bone marrow (BM), mobilized peripheral blood (mPB) and umbilical cord blood (UCB). Under appropriate conditions, VSELs in vitro and in vi...

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Bibliographic Details
Main Authors: Justyna Jarczak, Kamila Bujko, Mariusz Z. Ratajczak, Magdalena Kucia
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Umbilical cord blood VSELs
Single cell sequencing
RNA sequencing
Adult stem cells
Pluripotency
Transcriptome
Online Access:https://doi.org/10.1038/s41598-024-79810-4
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