Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China

Abstract Background Different areas of sheep infected with different types of parasites, all will cause serious harm to the local sheep, and the widespread use and repeated use of anthelmintics have produced different degrees of anthelmintic resistance (AR) in various regions. We re-investigated the...

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Main Authors: Yanmin Zhang, Weijie Wu, Zhiming Bai, Hao Zhang, Hao Liu, Lili Zhang, Chagan Luo, Mulan Chen, Jing Lu, Wa Gao, Wenlong Wang, Chunxia Liu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Veterinary Research
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Online Access:https://doi.org/10.1186/s12917-024-04420-1
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author Yanmin Zhang
Weijie Wu
Zhiming Bai
Hao Zhang
Hao Liu
Lili Zhang
Chagan Luo
Mulan Chen
Jing Lu
Wa Gao
Wenlong Wang
Chunxia Liu
author_facet Yanmin Zhang
Weijie Wu
Zhiming Bai
Hao Zhang
Hao Liu
Lili Zhang
Chagan Luo
Mulan Chen
Jing Lu
Wa Gao
Wenlong Wang
Chunxia Liu
author_sort Yanmin Zhang
collection DOAJ
description Abstract Background Different areas of sheep infected with different types of parasites, all will cause serious harm to the local sheep, and the widespread use and repeated use of anthelmintics have produced different degrees of anthelmintic resistance (AR) in various regions. We re-investigated the infection of common parasites and AR of Gastrointestinal Nematodes (GINs) in sheep in Horqin Right Wing Front Banner, and first investigated the common parasite types and AR of GINs in sheep at other four areas in Hinggan league (city), China. Results A total of 1770 fecal samples were collected from 1 prefecture-level city and 4 counties in Hinggan league, in which the infection rate of Coccidia ranged from 83.3% to 96.06%, that of Ascaris ovis ranged from 10.17% to 15.19%, that of Moniezia benedeni ranged from 0.6% to 1%, that of Moniezia expansa ranged from 0.33% to 8.15%. The infection rate of GINs was 100%, and Haemonchus contortus was still the dominant species. The AR results showed that only the closantel in Horqin Right Wing Middle Banner was low resiatant, and the other three regions had been resistant. Levamisole also occurred AR in the other four regions, the widely used ivermectin and albendazole had produced serious AR in five areas. The research shows that GINs are becoming more and more resistant to various anthelmintics, which has made the problem worse. Conclusions Understanding the dynamic changes of parasite infections and the development trend of AR in sheep in the region in this paper, the development trend seems to be more serious than imagined. Therefore only by deeply understanding the parasitic infections of sheep in this land can more reasonable medication guidance be carried out. It is expected to provide new ideas formore innovative, scientific and sustainable methods of preventing and controlling parasites.
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spelling doaj-art-9ec01be734174b33a990b52ec5d64c122025-08-20T02:31:41ZengBMCBMC Veterinary Research1746-61482024-12-0120111510.1186/s12917-024-04420-1Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), ChinaYanmin Zhang0Weijie Wu1Zhiming Bai2Hao Zhang3Hao Liu4Lili Zhang5Chagan Luo6Mulan Chen7Jing Lu8Wa Gao9Wenlong Wang10Chunxia Liu11College of Veterinary Medicine, Inner Mongolia Agricultural UniversityHinggan League Agricultural and Animal Husbandry Technology Extension CentreHorqin Right Front Banner Animal Disease Prevention and Control CenterCollege of Veterinary Medicine, Inner Mongolia Agricultural UniversityCollege of Veterinary Medicine, Inner Mongolia Agricultural UniversityCollege of Veterinary Medicine, Inner Mongolia Agricultural UniversityHinggan League Agricultural and Animal Husbandry Technology Extension CentreHinggan League Agricultural and Animal Husbandry Technology Extension CentreCollege of Veterinary Medicine, Inner Mongolia Agricultural UniversityHetao College and Inner Mongolia Key Laboratory of Tick-Borne Infectious DiseasesCollege of Veterinary Medicine, Inner Mongolia Agricultural UniversityCollege of Life Science, Inner Mongolia Agricultural UniversityAbstract Background Different areas of sheep infected with different types of parasites, all will cause serious harm to the local sheep, and the widespread use and repeated use of anthelmintics have produced different degrees of anthelmintic resistance (AR) in various regions. We re-investigated the infection of common parasites and AR of Gastrointestinal Nematodes (GINs) in sheep in Horqin Right Wing Front Banner, and first investigated the common parasite types and AR of GINs in sheep at other four areas in Hinggan league (city), China. Results A total of 1770 fecal samples were collected from 1 prefecture-level city and 4 counties in Hinggan league, in which the infection rate of Coccidia ranged from 83.3% to 96.06%, that of Ascaris ovis ranged from 10.17% to 15.19%, that of Moniezia benedeni ranged from 0.6% to 1%, that of Moniezia expansa ranged from 0.33% to 8.15%. The infection rate of GINs was 100%, and Haemonchus contortus was still the dominant species. The AR results showed that only the closantel in Horqin Right Wing Middle Banner was low resiatant, and the other three regions had been resistant. Levamisole also occurred AR in the other four regions, the widely used ivermectin and albendazole had produced serious AR in five areas. The research shows that GINs are becoming more and more resistant to various anthelmintics, which has made the problem worse. Conclusions Understanding the dynamic changes of parasite infections and the development trend of AR in sheep in the region in this paper, the development trend seems to be more serious than imagined. Therefore only by deeply understanding the parasitic infections of sheep in this land can more reasonable medication guidance be carried out. It is expected to provide new ideas formore innovative, scientific and sustainable methods of preventing and controlling parasites.https://doi.org/10.1186/s12917-024-04420-1Sheep parasitesPositivity ratesGastrointestinal nematodesHaemonchus contortusAnthelmintic resistanceHinggan League
spellingShingle Yanmin Zhang
Weijie Wu
Zhiming Bai
Hao Zhang
Hao Liu
Lili Zhang
Chagan Luo
Mulan Chen
Jing Lu
Wa Gao
Wenlong Wang
Chunxia Liu
Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China
BMC Veterinary Research
Sheep parasites
Positivity rates
Gastrointestinal nematodes
Haemonchus contortus
Anthelmintic resistance
Hinggan League
title Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China
title_full Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China
title_fullStr Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China
title_full_unstemmed Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China
title_short Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China
title_sort investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in hinggan league city china
topic Sheep parasites
Positivity rates
Gastrointestinal nematodes
Haemonchus contortus
Anthelmintic resistance
Hinggan League
url https://doi.org/10.1186/s12917-024-04420-1
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