Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn

A new (Reversed Phase- High Performance Liquid chromatography) RP-HPLC method with Ultraviolet-Visible spectrophotometry has been optimized and validated for the simultaneous extraction and determination of antioxidants present in Iraqi calyces of Hibiscus Sabdraffia Linn. The method is based on usi...

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Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2018-12-01
Series:مجلة بغداد للعلوم
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Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2942
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description A new (Reversed Phase- High Performance Liquid chromatography) RP-HPLC method with Ultraviolet-Visible spectrophotometry has been optimized and validated for the simultaneous extraction and determination of antioxidants present in Iraqi calyces of Hibiscus Sabdraffia Linn. The method is based on using ultrasonic bath for extracting antioxidants. Limit of detection in μg/ml of Vitamin C, Sabdaretine, Gossypetine, Hibiscetine, Anthocyanins, Dephinidin-3-glucoside were113.8294×10-6,123.0453×10-6,70.3681×10-6,59.6730×10-6,148.1710×10-6,and125.3481×10-6 respectively. The concentration of antioxidants found in dry spacemen of calyces of Iraqi Hibiscus Sabdraffia Linn. under study: Vitamin C, Sabdaretine, Gossypetine, Hibiscetine, Anthocyanins, and Dephinidin-3-glucoside are 258.3 μg/g, 225.51 μg/g, 154.975 μg/g, 111.407 μg/g, 439.442 μg/g, and 185.729 μg/g respectively.
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institution Kabale University
issn 2078-8665
2411-7986
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publishDate 2018-12-01
publisher University of Baghdad, College of Science for Women
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series مجلة بغداد للعلوم
spelling doaj-art-9ebc96cad9734e95956195a0301ff5962025-08-20T03:57:03ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862018-12-0112110.21123/bsj.12.1.119-126Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia LinnBaghdad Science JournalA new (Reversed Phase- High Performance Liquid chromatography) RP-HPLC method with Ultraviolet-Visible spectrophotometry has been optimized and validated for the simultaneous extraction and determination of antioxidants present in Iraqi calyces of Hibiscus Sabdraffia Linn. The method is based on using ultrasonic bath for extracting antioxidants. Limit of detection in μg/ml of Vitamin C, Sabdaretine, Gossypetine, Hibiscetine, Anthocyanins, Dephinidin-3-glucoside were113.8294×10-6,123.0453×10-6,70.3681×10-6,59.6730×10-6,148.1710×10-6,and125.3481×10-6 respectively. The concentration of antioxidants found in dry spacemen of calyces of Iraqi Hibiscus Sabdraffia Linn. under study: Vitamin C, Sabdaretine, Gossypetine, Hibiscetine, Anthocyanins, and Dephinidin-3-glucoside are 258.3 μg/g, 225.51 μg/g, 154.975 μg/g, 111.407 μg/g, 439.442 μg/g, and 185.729 μg/g respectively.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2942antioxidants, Hibiscus Sabdraffia Linn
spellingShingle Baghdad Science Journal
Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn
مجلة بغداد للعلوم
antioxidants, Hibiscus Sabdraffia Linn
title Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn
title_full Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn
title_fullStr Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn
title_full_unstemmed Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn
title_short Optimization and Validation of RP-HPLC-UV/VIS Method for Determination Some Antioxidants in Dry Calyces of Iraqi Hibiscus Sabdraffia Linn
title_sort optimization and validation of rp hplc uv vis method for determination some antioxidants in dry calyces of iraqi hibiscus sabdraffia linn
topic antioxidants, Hibiscus Sabdraffia Linn
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2942
work_keys_str_mv AT baghdadsciencejournal optimizationandvalidationofrphplcuvvismethodfordeterminationsomeantioxidantsindrycalycesofiraqihibiscussabdraffialinn