Calboxyvinyl polymer adjuvant enhances respiratory IgA responses through mucosal and systemic administration

Abstract Adjuvants play a crucial role in enhancing vaccine efficacy. Although several adjuvants have been approved, there remains a demand for safer and more effective adjuvants for nasal vaccines. Here, we identified calboxyvinyl polymer (CVP) as a superior mucosal vaccine adjuvant from pharmaceut...

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Bibliographic Details
Main Authors: Eita Sasaki, Hideki Asanuma, Haruka Momose, Jun–ichi Maeyama, Saya Moriyama, Noriyo Nagata, Tadaki Suzuki, Isao Hamaguchi, Hideki Hasegawa, Yoshimasa Takahashi
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01086-0
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