The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection
Noninvasive blood glucose monitoring is crucial for diabetes management, and photoacoustic spectroscopy (PAS) offers a promising solution by detecting glucose levels through human skin. However, weak acoustic signals in PAS systems require optimized resonator designs for enhanced detection sensitivi...
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MDPI AG
2025-04-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/15/4/254 |
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| author | Thasin Mohammad Zaman Md Rejvi Kaysir Shazzad Rassel Dayan Ban |
| author_facet | Thasin Mohammad Zaman Md Rejvi Kaysir Shazzad Rassel Dayan Ban |
| author_sort | Thasin Mohammad Zaman |
| collection | DOAJ |
| description | Noninvasive blood glucose monitoring is crucial for diabetes management, and photoacoustic spectroscopy (PAS) offers a promising solution by detecting glucose levels through human skin. However, weak acoustic signals in PAS systems require optimized resonator designs for enhanced detection sensitivity. Designing such resonators physically is complex, requiring the precise identification of critical parameters before practical implementation. This study focused on optimizing a T-shaped photoacoustic resonator using finite element modeling in a COMSOL Multiphysics environment. By systematically varying the geometric design parameters of the T-cell resonator, a maximum increase in the pressure amplitude of 12.76 times with a quality factor (Q-factor) of 47.5 was achieved compared to the previously designed reference acoustic resonator. This study took a significant step forward by identifying key geometric parameters that influence resonator performance, paving the way for more sensitive and reliable noninvasive glucose monitoring systems. |
| format | Article |
| id | doaj-art-9eb092b3de2a43c8a729ea996eb259e9 |
| institution | OA Journals |
| issn | 2079-6374 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj-art-9eb092b3de2a43c8a729ea996eb259e92025-08-20T02:17:25ZengMDPI AGBiosensors2079-63742025-04-0115425410.3390/bios15040254The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose DetectionThasin Mohammad Zaman0Md Rejvi Kaysir1Shazzad Rassel2Dayan Ban3Department of Electrical and Electronic Engineering (EEE), Khulna University of Engineering & Technology (KUET), Khulna 9203, BangladeshDepartment of Electrical and Electronic Engineering (EEE), Khulna University of Engineering & Technology (KUET), Khulna 9203, BangladeshDepartment of Electrical and Computer Engineering, Tennessee State University, 3500 John A Merritt Bivs, Nashville, TN 37209, USADepartment of Electrical and Computer Engineering, University of Waterloo, 200 University Ave. W, Waterloo, ON N2L 3G1, CanadaNoninvasive blood glucose monitoring is crucial for diabetes management, and photoacoustic spectroscopy (PAS) offers a promising solution by detecting glucose levels through human skin. However, weak acoustic signals in PAS systems require optimized resonator designs for enhanced detection sensitivity. Designing such resonators physically is complex, requiring the precise identification of critical parameters before practical implementation. This study focused on optimizing a T-shaped photoacoustic resonator using finite element modeling in a COMSOL Multiphysics environment. By systematically varying the geometric design parameters of the T-cell resonator, a maximum increase in the pressure amplitude of 12.76 times with a quality factor (Q-factor) of 47.5 was achieved compared to the previously designed reference acoustic resonator. This study took a significant step forward by identifying key geometric parameters that influence resonator performance, paving the way for more sensitive and reliable noninvasive glucose monitoring systems.https://www.mdpi.com/2079-6374/15/4/254photoacoustic spectroscopy (PAS)acoustic resonatorT-cellmid-infrared (MIR) spectroscopyQ-factorphotoacoustic resonator (PAR) |
| spellingShingle | Thasin Mohammad Zaman Md Rejvi Kaysir Shazzad Rassel Dayan Ban The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection Biosensors photoacoustic spectroscopy (PAS) acoustic resonator T-cell mid-infrared (MIR) spectroscopy Q-factor photoacoustic resonator (PAR) |
| title | The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection |
| title_full | The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection |
| title_fullStr | The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection |
| title_full_unstemmed | The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection |
| title_short | The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection |
| title_sort | optimization of a t cell resonator towards highly sensitive photoacoustic spectroscopy for noninvasive blood glucose detection |
| topic | photoacoustic spectroscopy (PAS) acoustic resonator T-cell mid-infrared (MIR) spectroscopy Q-factor photoacoustic resonator (PAR) |
| url | https://www.mdpi.com/2079-6374/15/4/254 |
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