The Safety and Immunogenicity of a 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/TT) in Infants: A Double-Blind, Randomized, Phase III Trial

The Safety and Immunogenicity of a 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/TT) in Infants: A Double-Blind, Randomized, Phase III Trial

Objectives: This study aimed to evaluate the immunogenicity and safety of a 13-valent pneumococcal polysaccharide conjugate vaccine (CRM197/TT) (PCV13i) in infants. Methods: A total of 1200 infants were randomly assigned to either the experimental PCV13i group or the control PCV13 group in a 1:1 rat...

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Bibliographic Details
Main Authors: Zhiqiang Xie, Jiangjiao Li, Xue Wang, Lili Huang, Jinbo Gou, Wei Zhang, Haitao Huang, Wangyang You, Feiyu Wang, Xiaolong Li, Jinming Zhang, Qiang Han, Xiaomin Ma, Yanxia Wang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Vaccines
Subjects:
13-valent pneumococcal polysaccharide conjugate vaccine
phase III trial
opsonophagocytic killing assay
infants
Online Access:https://www.mdpi.com/2076-393X/12/12/1417
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