Catheter-associated urinary tract infection in a surgical intensive care unit

Background/Aim. Because patients in intensive care units usually have an urinary catheter, the risk of urinary tract infection for these patients is higher than in other patients. The aim of this study was to identify risk factors and causative microrganisms in patients with catheter-associ...

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Main Authors: Mladenović Jovan, Veljović Milić, Udovičić Ivo, Lazić Srdjan, Jadranin Željko, Šegrt Zoran, Ristić Petar, Šuljagić Vesna
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2015-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500078M.pdf
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author Mladenović Jovan
Veljović Milić
Udovičić Ivo
Lazić Srdjan
Jadranin Željko
Šegrt Zoran
Ristić Petar
Šuljagić Vesna
author_facet Mladenović Jovan
Veljović Milić
Udovičić Ivo
Lazić Srdjan
Jadranin Željko
Šegrt Zoran
Ristić Petar
Šuljagić Vesna
author_sort Mladenović Jovan
collection DOAJ
description Background/Aim. Because patients in intensive care units usually have an urinary catheter, the risk of urinary tract infection for these patients is higher than in other patients. The aim of this study was to identify risk factors and causative microrganisms in patients with catheter-associated urinary tract infection (CAUTI) in the Surgical Intensive Care Unit (SICU) during a 6-year period. Methods. All data were collected during prospective surveillance conducted from 2006 to 2011 in the SICU, Military Medical Academy, Belgrade, Serbia. This case control study was performed in patients with nosocomial infections recorded during surveillance. The cases with CAUTIs were identified using the definition of the Center for Disease Control and Prevention. The control group consisted of patients with other nosocomial infections who did not fulfill criteria for CAUTIs according to case definition. Results. We surveyed 1,369 patients representing 13,761 patient days. There were a total of 226 patients with nosocomial infections in the SICU. Of these patients, 64 had CAUTIs as defined in this study, and 162 met the criteria for the control group. Multivariate logistic regression analysis identified two risk factors independently associated to CAUTIs: the duration of having an indwelling catheter (OR = 1.014; 95% CI 1.005-1.024; p = 0.003) and female gender (OR = 2.377; 95%CI 1.278-4.421; p = 0.006). Overall 71 pathogens were isolated from the urine culture of 64 patients with CAUTIs. Candida spp. (28.2%), Pseudomonas aeruginosa (18.3%) and Klebsiella spp. (15.5%) were the most frequently isolated microorganisms. Conclusions. The risk factors and causative microrganisms considering CAUTIs in the SICU must be considered in of planning CAUTIs prevention in this setting.
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spelling doaj-art-9ea32f5ac27d432785fe5600939ba52c2025-08-20T01:59:43ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202015-01-01721088388810.2298/VSP140624078M0042-84501500078MCatheter-associated urinary tract infection in a surgical intensive care unitMladenović Jovan0Veljović Milić1Udovičić Ivo2Lazić Srdjan3Jadranin Željko4Šegrt Zoran5Ristić Petar6Šuljagić Vesna7Military Medical Academy, Institute of Epidemiology, Belgrade, Serbia + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, SerbiaUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia + Military Medical Academy, Clinic for Anesthesiology and Intensive Care, Belgrade, SerbiaMilitary Medical Academy, Clinic for Anesthesiology and Intensive Care, Belgrade, SerbiaMilitary Medical Academy, Institute of Epidemiology, Belgrade, Serbia + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, SerbiaMilitary Medical Academy, Institute of Epidemiology, Belgrade, SerbiaUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia + Military Medical Academy, Sector for Treatment, Belgrade, SerbiaMilitary Medical Academy, Clinic for Endocrinology, Belgrade, SerbiaUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia + Military Medical Academy, Department of Hospital Infections Control, Belgrade, SerbiaBackground/Aim. Because patients in intensive care units usually have an urinary catheter, the risk of urinary tract infection for these patients is higher than in other patients. The aim of this study was to identify risk factors and causative microrganisms in patients with catheter-associated urinary tract infection (CAUTI) in the Surgical Intensive Care Unit (SICU) during a 6-year period. Methods. All data were collected during prospective surveillance conducted from 2006 to 2011 in the SICU, Military Medical Academy, Belgrade, Serbia. This case control study was performed in patients with nosocomial infections recorded during surveillance. The cases with CAUTIs were identified using the definition of the Center for Disease Control and Prevention. The control group consisted of patients with other nosocomial infections who did not fulfill criteria for CAUTIs according to case definition. Results. We surveyed 1,369 patients representing 13,761 patient days. There were a total of 226 patients with nosocomial infections in the SICU. Of these patients, 64 had CAUTIs as defined in this study, and 162 met the criteria for the control group. Multivariate logistic regression analysis identified two risk factors independently associated to CAUTIs: the duration of having an indwelling catheter (OR = 1.014; 95% CI 1.005-1.024; p = 0.003) and female gender (OR = 2.377; 95%CI 1.278-4.421; p = 0.006). Overall 71 pathogens were isolated from the urine culture of 64 patients with CAUTIs. Candida spp. (28.2%), Pseudomonas aeruginosa (18.3%) and Klebsiella spp. (15.5%) were the most frequently isolated microorganisms. Conclusions. The risk factors and causative microrganisms considering CAUTIs in the SICU must be considered in of planning CAUTIs prevention in this setting.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500078M.pdfurinary tract infectionscross infectionintensive care unitssurgery departmenthospitalrisk factorsurinary catheterization
spellingShingle Mladenović Jovan
Veljović Milić
Udovičić Ivo
Lazić Srdjan
Jadranin Željko
Šegrt Zoran
Ristić Petar
Šuljagić Vesna
Catheter-associated urinary tract infection in a surgical intensive care unit
Vojnosanitetski Pregled
urinary tract infections
cross infection
intensive care units
surgery department
hospital
risk factors
urinary catheterization
title Catheter-associated urinary tract infection in a surgical intensive care unit
title_full Catheter-associated urinary tract infection in a surgical intensive care unit
title_fullStr Catheter-associated urinary tract infection in a surgical intensive care unit
title_full_unstemmed Catheter-associated urinary tract infection in a surgical intensive care unit
title_short Catheter-associated urinary tract infection in a surgical intensive care unit
title_sort catheter associated urinary tract infection in a surgical intensive care unit
topic urinary tract infections
cross infection
intensive care units
surgery department
hospital
risk factors
urinary catheterization
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500078M.pdf
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