Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
An 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing Raoultella ornithinolytica. For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can l...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2023/5574769 |
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| _version_ | 1850179357636558848 |
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| author | Noriko Koishi Hiroshi Sasano Toshihiro Yoshizawa Mika Shikuri Hiroshi Matsumoto Mai Suzuki Yukiko Fukui Masayoshi Chonan Toshimi Kimura Hirofumi Ichida Akio Saiura Toshio Naito |
| author_facet | Noriko Koishi Hiroshi Sasano Toshihiro Yoshizawa Mika Shikuri Hiroshi Matsumoto Mai Suzuki Yukiko Fukui Masayoshi Chonan Toshimi Kimura Hirofumi Ichida Akio Saiura Toshio Naito |
| author_sort | Noriko Koishi |
| collection | DOAJ |
| description | An 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing Raoultella ornithinolytica. For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can lower the risk of adverse events and enable appropriate treatment. Key Clinical Message. When aminoglycoside antimicrobial agents are administered for MBL-producing bacteremia, prescription suggestions based on TDM by antimicrobial stewardship team can reduce the occurrence of adverse events and enable appropriate treatment. |
| format | Article |
| id | doaj-art-9e8fa3b5394c4d2dbc8302187dc7d166 |
| institution | OA Journals |
| issn | 2090-6633 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-9e8fa3b5394c4d2dbc8302187dc7d1662025-08-20T02:18:32ZengWileyCase Reports in Infectious Diseases2090-66332023-01-01202310.1155/2023/5574769Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin TreatmentNoriko Koishi0Hiroshi Sasano1Toshihiro Yoshizawa2Mika Shikuri3Hiroshi Matsumoto4Mai Suzuki5Yukiko Fukui6Masayoshi Chonan7Toshimi Kimura8Hirofumi Ichida9Akio Saiura10Toshio Naito11Department of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of General MedicineDepartment of General MedicineDepartment of Clinical LaboratoryDepartment of PharmacyDepartment of Hepatobiliary-Pancreatic SurgeryDepartment of Hepatobiliary-Pancreatic SurgeryDepartment of General MedicineAn 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing Raoultella ornithinolytica. For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can lower the risk of adverse events and enable appropriate treatment. Key Clinical Message. When aminoglycoside antimicrobial agents are administered for MBL-producing bacteremia, prescription suggestions based on TDM by antimicrobial stewardship team can reduce the occurrence of adverse events and enable appropriate treatment.http://dx.doi.org/10.1155/2023/5574769 |
| spellingShingle | Noriko Koishi Hiroshi Sasano Toshihiro Yoshizawa Mika Shikuri Hiroshi Matsumoto Mai Suzuki Yukiko Fukui Masayoshi Chonan Toshimi Kimura Hirofumi Ichida Akio Saiura Toshio Naito Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment Case Reports in Infectious Diseases |
| title | Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment |
| title_full | Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment |
| title_fullStr | Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment |
| title_full_unstemmed | Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment |
| title_short | Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment |
| title_sort | successful treatment of a case of metallo beta lactamase producing raoultella ornithinolytica bacteremia by antimicrobial stewardship team intervention and therapeutic drug monitoring based amikacin treatment |
| url | http://dx.doi.org/10.1155/2023/5574769 |
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