Human Granulocytic Anaplasmosis: First Reported Case in Canada

Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infection of peripheral blood neutrophils caused by Anaplasma phagocytophilum. While this infection is increasingly recognized as endemic throughout much of the United States, no Canadian cases have been previously described, despite...

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Main Authors: Michael D Parkins, Deirdre L Church, Xiu Yan Jiang, Daniel B Gregson
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2009/124173
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author Michael D Parkins
Deirdre L Church
Xiu Yan Jiang
Daniel B Gregson
author_facet Michael D Parkins
Deirdre L Church
Xiu Yan Jiang
Daniel B Gregson
author_sort Michael D Parkins
collection DOAJ
description Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infection of peripheral blood neutrophils caused by Anaplasma phagocytophilum. While this infection is increasingly recognized as endemic throughout much of the United States, no Canadian cases have been previously described, despite the agent being identified in Canadian ticks. Herein we present a case of HGA acquired in an urban Alberta centre. Canadian physicians must be aware of the possibility of tick-borne rickettsial diseases as etiology of fever in individuals presenting with leukopenia/lymphopenia, thrombocytopenia and elevated transaminases during periods of tick activity. Prompt recognition and treatment are important in minimizing resultant morbidity and mortality.
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publishDate 2009-01-01
publisher Wiley
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-9e8edea7bfc94bb892842f1d3fae15a22025-08-20T03:38:42ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322009-01-01203e100e10210.1155/2009/124173Human Granulocytic Anaplasmosis: First Reported Case in CanadaMichael D Parkins0Deirdre L Church1Xiu Yan Jiang2Daniel B Gregson3Department of Medicine, University of Calgary, CanadaDepartment of Medicine, University of Calgary, CanadaCalgary Laboratory Services, Calgary, Alberta, CanadaDepartment of Medicine, University of Calgary, CanadaHuman granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infection of peripheral blood neutrophils caused by Anaplasma phagocytophilum. While this infection is increasingly recognized as endemic throughout much of the United States, no Canadian cases have been previously described, despite the agent being identified in Canadian ticks. Herein we present a case of HGA acquired in an urban Alberta centre. Canadian physicians must be aware of the possibility of tick-borne rickettsial diseases as etiology of fever in individuals presenting with leukopenia/lymphopenia, thrombocytopenia and elevated transaminases during periods of tick activity. Prompt recognition and treatment are important in minimizing resultant morbidity and mortality.http://dx.doi.org/10.1155/2009/124173
spellingShingle Michael D Parkins
Deirdre L Church
Xiu Yan Jiang
Daniel B Gregson
Human Granulocytic Anaplasmosis: First Reported Case in Canada
Canadian Journal of Infectious Diseases and Medical Microbiology
title Human Granulocytic Anaplasmosis: First Reported Case in Canada
title_full Human Granulocytic Anaplasmosis: First Reported Case in Canada
title_fullStr Human Granulocytic Anaplasmosis: First Reported Case in Canada
title_full_unstemmed Human Granulocytic Anaplasmosis: First Reported Case in Canada
title_short Human Granulocytic Anaplasmosis: First Reported Case in Canada
title_sort human granulocytic anaplasmosis first reported case in canada
url http://dx.doi.org/10.1155/2009/124173
work_keys_str_mv AT michaeldparkins humangranulocyticanaplasmosisfirstreportedcaseincanada
AT deirdrelchurch humangranulocyticanaplasmosisfirstreportedcaseincanada
AT xiuyanjiang humangranulocyticanaplasmosisfirstreportedcaseincanada
AT danielbgregson humangranulocyticanaplasmosisfirstreportedcaseincanada