Automated 3D segmentation of the hyoid bone in CBCT using nnU-Net v2: a retrospective study on model performance and potential clinical utility

Abstract Objective This study aimed to identify the hyoid bone (HB) using the nnU-Net based artificial intelligence (AI) model in cone beam computed tomography (CBCT) images and assess the model’s success in automatic segmentation. Methods CBCT images of 190 patients were randomly selected. The raw...

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Bibliographic Details
Main Authors: Ismail Gümüssoy, Emre Haylaz, Suayip Burak Duman, Fahrettin Kalabalik, Seyda Say, Ozer Celik, Ibrahim Sevki Bayrakdar
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Imaging
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Online Access:https://doi.org/10.1186/s12880-025-01797-9
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Summary:Abstract Objective This study aimed to identify the hyoid bone (HB) using the nnU-Net based artificial intelligence (AI) model in cone beam computed tomography (CBCT) images and assess the model’s success in automatic segmentation. Methods CBCT images of 190 patients were randomly selected. The raw data was converted to DICOM format and transferred to the 3D Slicer Imaging Software (Version 4.10.2; MIT, Cambridge, MA, USA). HB was labeled manually using the 3D Slicer. The dataset was divided into training, validation, and test sets in a ratio of 8:1:1. The nnU-Net v2 architecture was utilized to process the training and test datasets, generating the algorithm weight factors. To assess the model’s accuracy and performance, a confusion matrix was employed. F1-score, Dice coefficient (DC), 95% Hausdorff distance (95% HD), and Intersection over Union (IoU) metrics were calculated to evaluate the results. Results The model’s performance metrics were as follows: DC = 0.9434, IoU = 0.8941, F1-score = 0.9446, and 95% HD = 1.9998. The receiver operating characteristic (ROC) curve was generated, yielding an AUC value of 0.98. Conclusion The results indicated that the nnU-Net v2 model achieved high precision and accuracy in HB segmentation on CBCT images. Automatic segmentation of HB can enhance clinicians’ decision-making speed and accuracy in diagnosing and treating various clinical conditions. Clinical trial number Not applicable.
ISSN:1471-2342