Neuroprotective Effect of Methylene Blue in a Rat Model of Traumatic Optic Neuropathy

Neuroprotective Effect of Methylene Blue in a Rat Model of Traumatic Optic Neuropathy

<b>Background</b>: Traumatic optic neuropathy (TON) represents a major cause of vision loss worldwide, and treatment options are limited. Here, we study whether methylene blue (MB), a free radical scavenger, is able to prevent morphological and electrophysiological hallmarks of neuropath...

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Main Authors: Nicolás S. Ciranna, Ronan Nakamura, Rafael Peláez, Álvaro Pérez-Sala, Patricia Sarrión, Juan C. Fernández, Alejandra Paganelli, Agustín P. Aranalde, Ulises P. Ruiz, Juan J. López-Costa, César F. Loidl, Alfredo Martínez, Manuel Rey-Funes
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
optic neuropathy
trauma
neuroprotection
methylene blue
electroretinography
retinal ganglion cells
Online Access:https://www.mdpi.com/1424-8247/18/6/920
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