Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review
The bacterial genus Myroides, like other members of the Flavobacteriaceae family, consists of aerobic, non-motile, Gram-negative bacilli. Myroides spp. is considered predominantly opportunistic pathogens as, historically, most documented infections have been in immunocompromised individuals. Along w...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2022/6422861 |
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| author | Melissa O’Neal Caitlin E. Labay Jesse E. Harris William L. Musick Patricia L. Cernoch Kevin A. Grimes Jiejian Lin Shivan Shah Elizabeth Ramos-Salazar |
| author_facet | Melissa O’Neal Caitlin E. Labay Jesse E. Harris William L. Musick Patricia L. Cernoch Kevin A. Grimes Jiejian Lin Shivan Shah Elizabeth Ramos-Salazar |
| author_sort | Melissa O’Neal |
| collection | DOAJ |
| description | The bacterial genus Myroides, like other members of the Flavobacteriaceae family, consists of aerobic, non-motile, Gram-negative bacilli. Myroides spp. is considered predominantly opportunistic pathogens as, historically, most documented infections have been in immunocompromised individuals. Along with advancements in molecular assay testing, there are growing reports of clinically relevant Myroides spp. infections in immunocompetent individuals. These organisms display broad antimicrobial resistance, and while research into their mechanisms of resistance is progressing, genetic testing has revealed metallo-β-lactamases present in their genome. The sporadic identification of Myroides spp. and ongoing clarification of resistance patterns make empiric treatment difficult. This report documents two cases of extensively drug-resistant Myroides odoratus isolated from critically ill but otherwise immunocompetent patients followed by a review of available literature on Myroides spp. antibiotic sensitivities. Our findings indicate that minocycline and moxifloxacin have the highest documented in vitro activity against Myroides spp. |
| format | Article |
| id | doaj-art-9e5a2c9292d5488486b2a5084ede0b47 |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-9e5a2c9292d5488486b2a5084ede0b472025-08-20T03:38:43ZengWileyCase Reports in Infectious Diseases2090-66332022-01-01202210.1155/2022/6422861Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature ReviewMelissa O’Neal0Caitlin E. Labay1Jesse E. Harris2William L. Musick3Patricia L. Cernoch4Kevin A. Grimes5Jiejian Lin6Shivan Shah7Elizabeth Ramos-Salazar8Department of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of Pathology and Genomic MedicineDivisions of Infectious DiseaseDivisions of Infectious DiseaseDivisions of Infectious DiseaseDivisions of Infectious DiseaseThe bacterial genus Myroides, like other members of the Flavobacteriaceae family, consists of aerobic, non-motile, Gram-negative bacilli. Myroides spp. is considered predominantly opportunistic pathogens as, historically, most documented infections have been in immunocompromised individuals. Along with advancements in molecular assay testing, there are growing reports of clinically relevant Myroides spp. infections in immunocompetent individuals. These organisms display broad antimicrobial resistance, and while research into their mechanisms of resistance is progressing, genetic testing has revealed metallo-β-lactamases present in their genome. The sporadic identification of Myroides spp. and ongoing clarification of resistance patterns make empiric treatment difficult. This report documents two cases of extensively drug-resistant Myroides odoratus isolated from critically ill but otherwise immunocompetent patients followed by a review of available literature on Myroides spp. antibiotic sensitivities. Our findings indicate that minocycline and moxifloxacin have the highest documented in vitro activity against Myroides spp.http://dx.doi.org/10.1155/2022/6422861 |
| spellingShingle | Melissa O’Neal Caitlin E. Labay Jesse E. Harris William L. Musick Patricia L. Cernoch Kevin A. Grimes Jiejian Lin Shivan Shah Elizabeth Ramos-Salazar Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review Case Reports in Infectious Diseases |
| title | Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review |
| title_full | Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review |
| title_fullStr | Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review |
| title_full_unstemmed | Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review |
| title_short | Extensively Drug-Resistant Myroides odoratus in Critically Ill Patients: A Case Series and Literature Review |
| title_sort | extensively drug resistant myroides odoratus in critically ill patients a case series and literature review |
| url | http://dx.doi.org/10.1155/2022/6422861 |
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