Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report

Guillain-Barré syndrome is an immune-mediated polyneuropathy that frequently presents with progressive muscle weakness. Hyponatremia has recently been described as a feature of this condition, generally appearing over the course of the illness and following the diagnosis of this demyelinating proce...

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Main Authors: Benjamin Kloesel, LaTonya J. Hickson
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/923602
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author Benjamin Kloesel
LaTonya J. Hickson
author_facet Benjamin Kloesel
LaTonya J. Hickson
author_sort Benjamin Kloesel
collection DOAJ
description Guillain-Barré syndrome is an immune-mediated polyneuropathy that frequently presents with progressive muscle weakness. Hyponatremia has recently been described as a feature of this condition, generally appearing over the course of the illness and following the diagnosis of this demyelinating process. We report a case of Guillain-Barré syndrome presenting with severe hyponatremia that is further exacerbated by intravenous immune globulin therapy. Awareness should be raised for consideration of both Guillain-Barré syndrome and its treatment with intravenous immune globulin therapy as the cause of hyponatremia.
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spelling doaj-art-9e59bde274994d92adbdd5ee1d65e3432025-08-20T02:18:32ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/923602923602Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case ReportBenjamin Kloesel0LaTonya J. Hickson1Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USAGuillain-Barré syndrome is an immune-mediated polyneuropathy that frequently presents with progressive muscle weakness. Hyponatremia has recently been described as a feature of this condition, generally appearing over the course of the illness and following the diagnosis of this demyelinating process. We report a case of Guillain-Barré syndrome presenting with severe hyponatremia that is further exacerbated by intravenous immune globulin therapy. Awareness should be raised for consideration of both Guillain-Barré syndrome and its treatment with intravenous immune globulin therapy as the cause of hyponatremia.http://dx.doi.org/10.1155/2013/923602
spellingShingle Benjamin Kloesel
LaTonya J. Hickson
Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report
Case Reports in Neurological Medicine
title Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report
title_full Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report
title_fullStr Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report
title_full_unstemmed Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report
title_short Severe Hyponatremia as the Initial Sign Preceding Guillain-Barré Syndrome, an Acute Inflammatory Demyelinating Polyneuropathy: A Case Report
title_sort severe hyponatremia as the initial sign preceding guillain barre syndrome an acute inflammatory demyelinating polyneuropathy a case report
url http://dx.doi.org/10.1155/2013/923602
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AT latonyajhickson severehyponatremiaastheinitialsignprecedingguillainbarresyndromeanacuteinflammatorydemyelinatingpolyneuropathyacasereport