Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis
Introduction The global incidence of patients with type 2 diabetes mellitus (T2DM) with dry eye is increasing annually, which imposes additional healthcare costs and financial burden on families and societies. In clinical practice, artificial tears are often used for symptomatic treatment, but these...
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e057289.full |
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| author | Ting Li Xin Xu Juan Wei Qingbo Wei Zhouyu Xie Xiangyu Bian Yunchuan Wu |
| author_facet | Ting Li Xin Xu Juan Wei Qingbo Wei Zhouyu Xie Xiangyu Bian Yunchuan Wu |
| author_sort | Ting Li |
| collection | DOAJ |
| description | Introduction The global incidence of patients with type 2 diabetes mellitus (T2DM) with dry eye is increasing annually, which imposes additional healthcare costs and financial burden on families and societies. In clinical practice, artificial tears are often used for symptomatic treatment, but these can only relieve the symptoms of discomfort. Acupuncture is a widely used alternative therapy. Indeed, randomised trials have found that acupuncture confers a definite therapeutic effect on patients with T2DM with dry eye. However, systematic reviews on the effectiveness and safety of acupuncture are lacking, therefore this systematic review aims to evaluate the effectiveness and safety of acupuncture for T2DM with dry eye.Methods and analysis Four English databases (PubMed, Cochrane Library, Embase and Ovid), three Chinese databases (China National Knowledge Infrastructure, Wanfang, Chonqing VIP Information), three Japanese databases (Japan Science, Technology Agency and Japan Medical Abstracts Society) and three Korean databases (Korean Medical database, Oriental Medicine Advanced Searching Integrated System and Research Information Service System) will be searched for reports published between 1 January 2007 and 1 October 2021. Only randomised controlled trials will be included, and language or publication dates will not be restricted. Two researchers will independently extract, manage and analyse data. The primary outcomes will include Schirmer’s I test, breakup time, corneal fluorescein staining and ocular surface disease index scores. Secondary results will include visual analogue scale scores for ocular symptoms and any adverse events related to acupuncture. We will use Review Manager V.5.4 for the meta-analysis. The risk of bias will be independently assessed using Cochrane’s ‘risk of bias’ tool.Ethics and dissemination Ethical approval will not be required since raw data will not be collected or generated. Our findings will be disseminated through peer-reviewed journal.PROSPERO registration number CRD42021271891. |
| format | Article |
| id | doaj-art-9e477eae976f440894439eb0bd81e2de |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-9e477eae976f440894439eb0bd81e2de2025-01-28T10:35:11ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-057289Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysisTing Li0Xin Xu1Juan Wei2Qingbo Wei3Zhouyu Xie4Xiangyu Bian5Yunchuan Wu62 Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaKey Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Zhongshan Hospital, Fudan University, Shanghai, ChinaAcupuncture and Massage College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaAcupuncture and Massage College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaAcupuncture and Massage College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaAcupuncture and Massage College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaAcupuncture and Massage College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaIntroduction The global incidence of patients with type 2 diabetes mellitus (T2DM) with dry eye is increasing annually, which imposes additional healthcare costs and financial burden on families and societies. In clinical practice, artificial tears are often used for symptomatic treatment, but these can only relieve the symptoms of discomfort. Acupuncture is a widely used alternative therapy. Indeed, randomised trials have found that acupuncture confers a definite therapeutic effect on patients with T2DM with dry eye. However, systematic reviews on the effectiveness and safety of acupuncture are lacking, therefore this systematic review aims to evaluate the effectiveness and safety of acupuncture for T2DM with dry eye.Methods and analysis Four English databases (PubMed, Cochrane Library, Embase and Ovid), three Chinese databases (China National Knowledge Infrastructure, Wanfang, Chonqing VIP Information), three Japanese databases (Japan Science, Technology Agency and Japan Medical Abstracts Society) and three Korean databases (Korean Medical database, Oriental Medicine Advanced Searching Integrated System and Research Information Service System) will be searched for reports published between 1 January 2007 and 1 October 2021. Only randomised controlled trials will be included, and language or publication dates will not be restricted. Two researchers will independently extract, manage and analyse data. The primary outcomes will include Schirmer’s I test, breakup time, corneal fluorescein staining and ocular surface disease index scores. Secondary results will include visual analogue scale scores for ocular symptoms and any adverse events related to acupuncture. We will use Review Manager V.5.4 for the meta-analysis. The risk of bias will be independently assessed using Cochrane’s ‘risk of bias’ tool.Ethics and dissemination Ethical approval will not be required since raw data will not be collected or generated. Our findings will be disseminated through peer-reviewed journal.PROSPERO registration number CRD42021271891.https://bmjopen.bmj.com/content/12/6/e057289.full |
| spellingShingle | Ting Li Xin Xu Juan Wei Qingbo Wei Zhouyu Xie Xiangyu Bian Yunchuan Wu Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis BMJ Open |
| title | Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis |
| title_full | Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis |
| title_fullStr | Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis |
| title_full_unstemmed | Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis |
| title_short | Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis |
| title_sort | acupuncture for patients with type 2 diabetes mellitus with dry eye protocol for a systematic review and meta analysis |
| url | https://bmjopen.bmj.com/content/12/6/e057289.full |
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