Bayesian Covariate-Dependent Circadian Modeling of Rest-Activity Rhythms

We propose a Bayesian covariate-dependent anti-logistic circadian model for analyzing activity data collected via wrist-worn wearable devices. The proposed approach integrates covariates into the modeling of the amplitude and phase parameters, facilitating cohort-level analysis with enhanced flexibi...

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Bibliographic Details
Main Authors: Beniamino Hadj-Amar, Vaishnav Krishnan, Marina Vannucci
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Data Science in Science
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Online Access:https://www.tandfonline.com/doi/10.1080/26941899.2025.2474943
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Summary:We propose a Bayesian covariate-dependent anti-logistic circadian model for analyzing activity data collected via wrist-worn wearable devices. The proposed approach integrates covariates into the modeling of the amplitude and phase parameters, facilitating cohort-level analysis with enhanced flexibility and interpretability. To promote model sparsity, we employ an [Formula: see text]-ball projection prior, enabling precise control over complexity while identifying significant predictors. We assess performances on simulated data and then apply the method to real-world actigraphy data from people with epilepsy. Our results demonstrate the model’s effectiveness in uncovering complex relationships among demographic, psychological, and medical factors influencing rest-activity rhythms, offering insights for personalized clinical assessments and healthcare interventions.
ISSN:2694-1899