Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling

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Main Authors: Yaya Du, Jingcheng Yang, Fei Li, Linxi Wang, Yiyuan Tian, Le Yang, Lanxin Luo
Format: Article
Language:English
Published: American Chemical Society 2025-06-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.5c02585
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author Yaya Du
Jingcheng Yang
Fei Li
Linxi Wang
Yiyuan Tian
Le Yang
Lanxin Luo
author_facet Yaya Du
Jingcheng Yang
Fei Li
Linxi Wang
Yiyuan Tian
Le Yang
Lanxin Luo
author_sort Yaya Du
collection DOAJ
format Article
id doaj-art-9e214989f6b94a8293af41d574a3f85d
institution DOAJ
issn 2470-1343
language English
publishDate 2025-06-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-9e214989f6b94a8293af41d574a3f85d2025-08-20T02:41:39ZengAmerican Chemical SocietyACS Omega2470-13432025-06-011027294282944110.1021/acsomega.5c02585Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT SignalingYaya Du0Jingcheng Yang1Fei Li2Linxi Wang3Yiyuan Tian4Le Yang5Lanxin Luo6Precision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, the Fourth Military Medical University, Xi’an, Shaanxi, PR ChinaPrecision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, the Fourth Military Medical University, Xi’an, Shaanxi, PR ChinaDepartment of Toxicology, Shanxi Provincial Key Lab of Free Radical Biology and Medicine, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, the Fourth Military Medical University, Xi’an, Shaanxi, PR ChinaPrecision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, the Fourth Military Medical University, Xi’an, Shaanxi, PR ChinaDepartment of Cardiology, Xijing Hospital, the Fourth Military Medical University, Xi’an, Shaanxi, PR ChinaPrecision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, the Fourth Military Medical University, Xi’an, Shaanxi, PR ChinaPrecision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, the Fourth Military Medical University, Xi’an, Shaanxi, PR Chinahttps://doi.org/10.1021/acsomega.5c02585
spellingShingle Yaya Du
Jingcheng Yang
Fei Li
Linxi Wang
Yiyuan Tian
Le Yang
Lanxin Luo
Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling
ACS Omega
title Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling
title_full Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling
title_fullStr Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling
title_full_unstemmed Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling
title_short Alleviation of Depression-Like Symptoms Through Orientin-Mediated Regulation of Neuroinflammation and PI3K/AKT Signaling
title_sort alleviation of depression like symptoms through orientin mediated regulation of neuroinflammation and pi3k akt signaling
url https://doi.org/10.1021/acsomega.5c02585
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