Thrombocytopenia in Liver Disease
Moderate thrombocytopenia is a frequent finding in cirrhosis of the liver and well tolerated in most instances. The pathophysiology of thrombocytopenia in liver disease has long been associated with the concept of hypersplenism, where portal hypertension was thought to cause pooling and sequestratio...
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2000-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2000/617428 |
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| _version_ | 1850170499698524160 |
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| author | Markus Peck-Radosavljevic |
| author_facet | Markus Peck-Radosavljevic |
| author_sort | Markus Peck-Radosavljevic |
| collection | DOAJ |
| description | Moderate thrombocytopenia
is a frequent finding in cirrhosis of the liver and well
tolerated in most instances. The pathophysiology of thrombocytopenia
in liver disease has long been associated with the concept
of hypersplenism, where portal hypertension was thought to cause
pooling and sequestration of all corpuscular elements of the blood,
predominantly thrombocytes in the enlarged spleen. The concept of
hypersplenism was never proven beyond any doubt but was widely
accepted for the lack of alternative explanations. |
| format | Article |
| id | doaj-art-9e152c52316343a49dee1a5ea63cf2b9 |
| institution | OA Journals |
| issn | 0835-7900 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-9e152c52316343a49dee1a5ea63cf2b92025-08-20T02:20:29ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-0114Suppl D60D66D10.1155/2000/617428Thrombocytopenia in Liver DiseaseMarkus Peck-Radosavljevic0Department of Gastroenterology and Hepatology, University of Vienna Medical School, Vienna, AustriaModerate thrombocytopenia is a frequent finding in cirrhosis of the liver and well tolerated in most instances. The pathophysiology of thrombocytopenia in liver disease has long been associated with the concept of hypersplenism, where portal hypertension was thought to cause pooling and sequestration of all corpuscular elements of the blood, predominantly thrombocytes in the enlarged spleen. The concept of hypersplenism was never proven beyond any doubt but was widely accepted for the lack of alternative explanations.http://dx.doi.org/10.1155/2000/617428 |
| spellingShingle | Markus Peck-Radosavljevic Thrombocytopenia in Liver Disease Canadian Journal of Gastroenterology |
| title | Thrombocytopenia in Liver Disease |
| title_full | Thrombocytopenia in Liver Disease |
| title_fullStr | Thrombocytopenia in Liver Disease |
| title_full_unstemmed | Thrombocytopenia in Liver Disease |
| title_short | Thrombocytopenia in Liver Disease |
| title_sort | thrombocytopenia in liver disease |
| url | http://dx.doi.org/10.1155/2000/617428 |
| work_keys_str_mv | AT markuspeckradosavljevic thrombocytopeniainliverdisease |