Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years
Background: Unprovoked seizures in children, occurring without immediate precipitating factors, pose significant challenges due to their potential to recur. Objectives: This study aims to identify clinical profile and predictors of recurrence in children aged 1 month to 12 years presenting with thei...
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Al Ameen Medical College
2025-01-01
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| Series: | Al Ameen Journal of Medical Sciences |
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| Online Access: | https://ajms.alameenmedical.org/ArticlePDFs/11%20AJMS%20V18.N1.2025%20p%2060-65.pdf |
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| author | Ambili Susan Jacob Urmila K.V |
| author_facet | Ambili Susan Jacob Urmila K.V |
| author_sort | Ambili Susan Jacob |
| collection | DOAJ |
| description | Background: Unprovoked seizures in children, occurring without immediate precipitating factors, pose significant challenges due to their potential to recur. Objectives: This study aims to identify clinical profile and predictors of recurrence in children aged 1 month to 12 years presenting with their first unprovoked seizure. Methods: Conducted over one and a half years in a tertiary care hospital in North Kerala, the study included 61 children. Data on seizure characteristics, past medical history, EEG and neuroimaging findings, and recurrence rates were analysed. Results: It was revealed that there is a 52% recurrence rate, with the highest recurrence occurring within the first 3 months (71.9%). Significant predictors of recurrence included seizures occurring during sleep, a history of neurological insults, developmental delay or intellectual disability, and abnormal EEG or neuroimaging findings. Factors such as age, gender, type of seizure, and status epilepticus did not significantly impact recurrence risk. Conclusions: The study underscores the importance of identifying these predictors for optimizing treatment and monitoring strategies. Close follow-up is recommended for children with identified risk factors to enhance management and improve long-term outcomes. |
| format | Article |
| id | doaj-art-9e0dd32a4e0d476abda36986efe2b8f3 |
| institution | Kabale University |
| issn | 0974-1143 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Al Ameen Medical College |
| record_format | Article |
| series | Al Ameen Journal of Medical Sciences |
| spelling | doaj-art-9e0dd32a4e0d476abda36986efe2b8f32025-01-11T12:26:52ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432025-01-0118016065Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 yearsAmbili Susan Jacob0Urmila K.V1Department of Paediatrics, Government Medical College, Kannur-670502, Kerala, IndiaDepartment of Paediatrics, Government Medical College, Kannur-670502, Kerala, IndiaBackground: Unprovoked seizures in children, occurring without immediate precipitating factors, pose significant challenges due to their potential to recur. Objectives: This study aims to identify clinical profile and predictors of recurrence in children aged 1 month to 12 years presenting with their first unprovoked seizure. Methods: Conducted over one and a half years in a tertiary care hospital in North Kerala, the study included 61 children. Data on seizure characteristics, past medical history, EEG and neuroimaging findings, and recurrence rates were analysed. Results: It was revealed that there is a 52% recurrence rate, with the highest recurrence occurring within the first 3 months (71.9%). Significant predictors of recurrence included seizures occurring during sleep, a history of neurological insults, developmental delay or intellectual disability, and abnormal EEG or neuroimaging findings. Factors such as age, gender, type of seizure, and status epilepticus did not significantly impact recurrence risk. Conclusions: The study underscores the importance of identifying these predictors for optimizing treatment and monitoring strategies. Close follow-up is recommended for children with identified risk factors to enhance management and improve long-term outcomes.https://ajms.alameenmedical.org/ArticlePDFs/11%20AJMS%20V18.N1.2025%20p%2060-65.pdfunprovoked seizuresclinical profilepredictorsrecurrence |
| spellingShingle | Ambili Susan Jacob Urmila K.V Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years Al Ameen Journal of Medical Sciences unprovoked seizures clinical profile predictors recurrence |
| title | Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years |
| title_full | Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years |
| title_fullStr | Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years |
| title_full_unstemmed | Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years |
| title_short | Clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years |
| title_sort | clinical profile and predictors of recurrence of first episode of unprovoked seizures in children of the age group 1 month to 12 years |
| topic | unprovoked seizures clinical profile predictors recurrence |
| url | https://ajms.alameenmedical.org/ArticlePDFs/11%20AJMS%20V18.N1.2025%20p%2060-65.pdf |
| work_keys_str_mv | AT ambilisusanjacob clinicalprofileandpredictorsofrecurrenceoffirstepisodeofunprovokedseizuresinchildrenoftheagegroup1monthto12years AT urmilakv clinicalprofileandpredictorsofrecurrenceoffirstepisodeofunprovokedseizuresinchildrenoftheagegroup1monthto12years |