Microbial melatonin metabolism in the human intestine as a therapeutic target for dysbiosis and rhythm disorders
Abstract Melatonin (MT) (N-acetyl-5-methoxytryptamine) is an indoleamine recognized primarily for its crucial role in regulating sleep through circadian rhythm modulation in humans and animals. Beyond its association with the pineal gland, it is synthesized in various tissues, functioning as a hormo...
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| Main Authors: | Petra Zimmermann, Salome Kurth, Benoit Pugin, Nicholas A. Bokulich |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | npj Biofilms and Microbiomes |
| Online Access: | https://doi.org/10.1038/s41522-024-00605-6 |
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