α-Mangostin Exhibits Antitumor Activity Against NCI-H1975 Cells via the EGFR/STAT3 Pathway: An Experimental and Molecular Simulation Study

α-Mangostin Exhibits Antitumor Activity Against NCI-H1975 Cells via the EGFR/STAT3 Pathway: An Experimental and Molecular Simulation Study

Non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations have brought great challenges to the medical treatment in the world. Current treatment strategies, such as EGFR tyrosine kinase inhibitors (TKIs), have reached certain achievements, however, patients inevi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jing Wang, Jiamin Xian, Ruohan Zhang, Zhuoyi Wang, Shuanggou Zhang, Die Zhao, Jun Sheng, Peiyuan Sun
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
NSCLC
EGFR
α-Mangostin
antitumor activity
molecular simulation
Online Access:https://www.mdpi.com/1420-3049/30/6/1294
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items