Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study
Objective Poor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD.Design This...
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BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/12/e074025.full |
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| author | Manmak Mamven Oluseyi Ademola Adejumo Imuetinyan Rashida Edeki Olawale Stephen Oguntola Ogochukwu Chinedum Okoye Akinwumi Ayodeji Akinbodewa Enajite Ibiene Okaka Sulaiman Dazumi Ahmed Oghenekaro Gódwin Egbi Joshua Falade Samuel Ayokunle Dada Monday Ogiagah Ogiator Barbara Okoh |
| author_facet | Manmak Mamven Oluseyi Ademola Adejumo Imuetinyan Rashida Edeki Olawale Stephen Oguntola Ogochukwu Chinedum Okoye Akinwumi Ayodeji Akinbodewa Enajite Ibiene Okaka Sulaiman Dazumi Ahmed Oghenekaro Gódwin Egbi Joshua Falade Samuel Ayokunle Dada Monday Ogiagah Ogiator Barbara Okoh |
| author_sort | Manmak Mamven |
| collection | DOAJ |
| description | Objective Poor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD.Design This was a cross-sectional study that involved patients with CKD .Settings The study was carried out in the outpatient clinic of nine hospitals in Nigeria.Methods Sleep quality, depressive and anxiety symptoms and quality of life (QoL) were assessed among 307 patients with CKD using Pittsburgh Sleep Quality Index Questionnaire, Hospital Anxiety Depression Scale Questionnaire and 12-item Short Form Health Survey Quality of Life Questionnaire, respectively. The prevalence of poor sleep quality and associated factors were determined. A p<0.05 was considered as statistically significant.Results The mean age of the study participants was 51.40±15.17 years. The male:female ratio was 1.5:1 One hundred and twenty-one (39.4%) of the patients were on maintenance haemodialysis (MHD). The prevalence of poor sleep quality, anxiety symptoms and depressive symptoms among the patients was 50.2%, 37.8% and 17.6%, respectively. The prevalence of poor sleep quality in the CKD stages 3, 4, 5 and 5D was 38.1%, 42.6%, 52.2% and 58.7%, respectively. The prevalence of poor sleep quality was significantly higher in MHD patients compared with predialysis CKD (59.5% vs 43.6%; p=0.008). Factors associated with poor sleep quality were CKD stage (p=0.035), anaemia (p=0.003), pruritus (p=0.045), anxiety symptoms (p≤0.001), depressive symptoms (p≤0.001) and reduced QoL (p≤0.001). On multivariate analysis, factors associated with poor sleep were anxiety (AOR 2.19; 95% CI 1.27 to 3.79; p=0.005), anaemia (AOR 5.49; 95% CI 1.43 to 21.00;p=0.013) and reduced physical component of QoL (AOR 4.11; 95% CI 1.61 to 10.47; p=0.003).Conclusion Poor sleep quality is common among patients with CKD especially in the advanced stage. The significant factors associated with poor sleep quality were QoL, anaemia and anxiety symptoms. These factors should be adequately managed to improve the overall outcomes of patients with CKD. |
| format | Article |
| id | doaj-art-9dff74ffa7124677a1b35d2f36eed2dc |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-9dff74ffa7124677a1b35d2f36eed2dc2025-08-20T03:52:28ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-074025Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional studyManmak Mamven0Oluseyi Ademola Adejumo1Imuetinyan Rashida Edeki2Olawale Stephen Oguntola3Ogochukwu Chinedum Okoye4Akinwumi Ayodeji Akinbodewa5Enajite Ibiene Okaka6Sulaiman Dazumi Ahmed7Oghenekaro Gódwin Egbi8Joshua Falade9Samuel Ayokunle Dada10Monday Ogiagah Ogiator11Barbara Okoh12Department of Internal Medicine, University of Abuja, Abuja, NigeriaDepartment of Internal Medicine, University of Medical Sciences, Ondo City, NigeriaUniversity of Benin Teaching Hospital, Benin City, Edo, NigeriaDepartment of Internal Medicine, Afe Babalola University, Ado Ekiti, NigeriaDepartment of Internal Medicine, Delta State University, Abraka, NigeriaDepartment of Internal Medicine, University of Medical Sciences, Ondo City, NigeriaDepartment of Internal Medicine, University of Benin, Benin City, NigeriaDepartment of Internal Medicine, Irrua Specialist Teaching Hospital, Irrua, NigeriaDepartment of Internal Medicine, Niger Delta University, Okolobiri, NigeriaDepartment of Internal Medicine, University of Medical Sciences, Ondo City, NigeriaDepartment of Internal Medicine, Ekiti State University, Ado Ekiti, NigeriaDepartment of Internal Medicine, Benue State University, Makurdi, NigeriaDepartment of Internal Medicine, Irrua Specialist Teaching Hospital, Irrua, NigeriaObjective Poor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD.Design This was a cross-sectional study that involved patients with CKD .Settings The study was carried out in the outpatient clinic of nine hospitals in Nigeria.Methods Sleep quality, depressive and anxiety symptoms and quality of life (QoL) were assessed among 307 patients with CKD using Pittsburgh Sleep Quality Index Questionnaire, Hospital Anxiety Depression Scale Questionnaire and 12-item Short Form Health Survey Quality of Life Questionnaire, respectively. The prevalence of poor sleep quality and associated factors were determined. A p<0.05 was considered as statistically significant.Results The mean age of the study participants was 51.40±15.17 years. The male:female ratio was 1.5:1 One hundred and twenty-one (39.4%) of the patients were on maintenance haemodialysis (MHD). The prevalence of poor sleep quality, anxiety symptoms and depressive symptoms among the patients was 50.2%, 37.8% and 17.6%, respectively. The prevalence of poor sleep quality in the CKD stages 3, 4, 5 and 5D was 38.1%, 42.6%, 52.2% and 58.7%, respectively. The prevalence of poor sleep quality was significantly higher in MHD patients compared with predialysis CKD (59.5% vs 43.6%; p=0.008). Factors associated with poor sleep quality were CKD stage (p=0.035), anaemia (p=0.003), pruritus (p=0.045), anxiety symptoms (p≤0.001), depressive symptoms (p≤0.001) and reduced QoL (p≤0.001). On multivariate analysis, factors associated with poor sleep were anxiety (AOR 2.19; 95% CI 1.27 to 3.79; p=0.005), anaemia (AOR 5.49; 95% CI 1.43 to 21.00;p=0.013) and reduced physical component of QoL (AOR 4.11; 95% CI 1.61 to 10.47; p=0.003).Conclusion Poor sleep quality is common among patients with CKD especially in the advanced stage. The significant factors associated with poor sleep quality were QoL, anaemia and anxiety symptoms. These factors should be adequately managed to improve the overall outcomes of patients with CKD.https://bmjopen.bmj.com/content/13/12/e074025.full |
| spellingShingle | Manmak Mamven Oluseyi Ademola Adejumo Imuetinyan Rashida Edeki Olawale Stephen Oguntola Ogochukwu Chinedum Okoye Akinwumi Ayodeji Akinbodewa Enajite Ibiene Okaka Sulaiman Dazumi Ahmed Oghenekaro Gódwin Egbi Joshua Falade Samuel Ayokunle Dada Monday Ogiagah Ogiator Barbara Okoh Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study BMJ Open |
| title | Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study |
| title_full | Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study |
| title_fullStr | Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study |
| title_full_unstemmed | Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study |
| title_short | Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study |
| title_sort | sleep quality and associated factors among patients with chronic kidney disease in nigeria a cross sectional study |
| url | https://bmjopen.bmj.com/content/13/12/e074025.full |
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