Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae)
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family. It has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. The antispasmodic activity was investigated in vitro using rabbit intestine, and the antioxidant activi...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/32/e3sconf_joe52025_01007.pdf |
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| author | Bendaif Hajar Melhaoui Ahmed Elouadi Yassir Essadki Samia Elmsellem Hicham Benali Taoufiq Aziz Mohammed Hafez Baraa Hachmi Azeddine Abrigach Farid |
| author_facet | Bendaif Hajar Melhaoui Ahmed Elouadi Yassir Essadki Samia Elmsellem Hicham Benali Taoufiq Aziz Mohammed Hafez Baraa Hachmi Azeddine Abrigach Farid |
| author_sort | Bendaif Hajar |
| collection | DOAJ |
| description | Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family. It has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. The antispasmodic activity was investigated in vitro using rabbit intestine, and the antioxidant activity was evaluated by DPPH assay. The results indicated that lycorine has an irreversible relaxant property on the isolated rabbit jejunum. Whereas, it did not show a significant antioxidant activity toward the DPPH free radical in comparison with ascorbic acid. |
| format | Article |
| id | doaj-art-9dfdbeed0914477b8f5153aca6406560 |
| institution | Kabale University |
| issn | 2267-1242 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj-art-9dfdbeed0914477b8f5153aca64065602025-08-20T03:45:04ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016320100710.1051/e3sconf/202563201007e3sconf_joe52025_01007Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae)Bendaif Hajar0Melhaoui Ahmed1Elouadi Yassir2Essadki Samia3Elmsellem Hicham4Benali Taoufiq5Aziz Mohammed6Hafez Baraa7Hachmi Azeddine8Abrigach Farid9Natural Resources and Environment Laboratory, Biology Chemistry Geology Department, Polydisciplinary Faculty of Taza, Sidi Mohamed Ben Abdellah UniversityLaboratory of Applied Chemistry and Environment –ECOMP, Faculty of Sciences, Mohamed 1st UniversityHigher Institute of Nurses Professions and Health Techniques of Agadir, Annex of Guelmim –Higher Institute of Nursing Professions and Health Techniques (ISPITSO)Higher Institute of Nursing Professions and Health Techniques (ISPITSO)Environment and Health Team, Polydisciplinary Faculty of Safi, Cadi Ayyad UniversityLaboratory of bioresources, biotechnology and health, faculty of sciences, mohammed first universityDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman UniversityDepartment of Biology, Mohammed v University, Faculty of ScienceLaboratory of Applied Chemistry and Environment (LCAE), Faculty of Sciences, Mohammed First UniversityLycorine is a natural alkaloid extracted from the Amaryllidaceae plant family. It has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. The antispasmodic activity was investigated in vitro using rabbit intestine, and the antioxidant activity was evaluated by DPPH assay. The results indicated that lycorine has an irreversible relaxant property on the isolated rabbit jejunum. Whereas, it did not show a significant antioxidant activity toward the DPPH free radical in comparison with ascorbic acid.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/32/e3sconf_joe52025_01007.pdf |
| spellingShingle | Bendaif Hajar Melhaoui Ahmed Elouadi Yassir Essadki Samia Elmsellem Hicham Benali Taoufiq Aziz Mohammed Hafez Baraa Hachmi Azeddine Abrigach Farid Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae) E3S Web of Conferences |
| title | Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae) |
| title_full | Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae) |
| title_fullStr | Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae) |
| title_full_unstemmed | Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae) |
| title_short | Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from Pancratium foetidum Pom. (Moroccan Endemic Amaryllidaceae) |
| title_sort | evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from pancratium foetidum pom moroccan endemic amaryllidaceae |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/32/e3sconf_joe52025_01007.pdf |
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