Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants

ObjectiveTo investigate the association between maternal infection with the SARS-CoV-2 Omicron variant during pregnancy and common infant illnesses and neurodevelopment.MethodsA cohort study was designed, selecting 113 pregnant women from Shanghai’s Pudong New Area who tested positive for SARS-CoV-2...

Full description

Saved in:
Bibliographic Details
Main Authors: XU Weiqing, LUO Dan, JIANG Hong, SHI Junyao
Format: Article
Language:zho
Published: Shanghai Preventive Medicine Association 2025-01-01
Series:Shanghai yufang yixue
Subjects:
Online Access:http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2025.24128?viewType=HTML
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850049522451873792
author XU Weiqing
LUO Dan
JIANG Hong
SHI Junyao
author_facet XU Weiqing
LUO Dan
JIANG Hong
SHI Junyao
author_sort XU Weiqing
collection DOAJ
description ObjectiveTo investigate the association between maternal infection with the SARS-CoV-2 Omicron variant during pregnancy and common infant illnesses and neurodevelopment.MethodsA cohort study was designed, selecting 113 pregnant women from Shanghai’s Pudong New Area who tested positive for SARS-CoV-2 by nasal swab reverse transcription-polymerase chain reaction (RT-PCR) and were transported to medical institutions for isolation treatment between March and May 2022. These women constituted the pregnancy infection group. Concurrently, 226 pregnant women from the same region and time period who did not infect with SARS-CoV-2 were selected as the control group. Both groups were followed up until delivery and their offspring’s one year old. The differences in the risk of common infant illnesses and the level of infant’s neurodevelopment at age one were compared between the two groups.ResultsNo significant difference was found in the incidence of common illnesses before one year of age between the pregnancy infection group and the control group. Additionally, no significant differences were found in any domain scores of the ASQ-3 between the two groups.ConclusionMaternal infection with SARS-CoV-2 Omicron variant during pregnancy was not statistically significant correlated with common infant illnesses in infancy and neurodevelopment at age one.
format Article
id doaj-art-9dfc6cb988d04f6fa6df0f212bafe0d6
institution DOAJ
issn 1004-9231
language zho
publishDate 2025-01-01
publisher Shanghai Preventive Medicine Association
record_format Article
series Shanghai yufang yixue
spelling doaj-art-9dfc6cb988d04f6fa6df0f212bafe0d62025-08-20T02:53:41ZzhoShanghai Preventive Medicine AssociationShanghai yufang yixue1004-92312025-01-01371343810.19428/j.cnki.sjpm.2025.241281004-9231(2025)01-0034-05Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infantsXU Weiqing0LUO Dan1JIANG Hong2SHI Junyao3Shanghai Pudong New Area Health Care Hospital for Women and Children (Shanghai Pudong Center for Women and Children's Health), Shanghai 201399, ChinaShanghai Pudong New Area Health Care Hospital for Women and Children (Shanghai Pudong Center for Women and Children's Health), Shanghai 201399, ChinaSchool of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai 200032, ChinaShanghai Pudong New Area Health Care Hospital for Women and Children (Shanghai Pudong Center for Women and Children's Health), Shanghai 201399, ChinaObjectiveTo investigate the association between maternal infection with the SARS-CoV-2 Omicron variant during pregnancy and common infant illnesses and neurodevelopment.MethodsA cohort study was designed, selecting 113 pregnant women from Shanghai’s Pudong New Area who tested positive for SARS-CoV-2 by nasal swab reverse transcription-polymerase chain reaction (RT-PCR) and were transported to medical institutions for isolation treatment between March and May 2022. These women constituted the pregnancy infection group. Concurrently, 226 pregnant women from the same region and time period who did not infect with SARS-CoV-2 were selected as the control group. Both groups were followed up until delivery and their offspring’s one year old. The differences in the risk of common infant illnesses and the level of infant’s neurodevelopment at age one were compared between the two groups.ResultsNo significant difference was found in the incidence of common illnesses before one year of age between the pregnancy infection group and the control group. Additionally, no significant differences were found in any domain scores of the ASQ-3 between the two groups.ConclusionMaternal infection with SARS-CoV-2 Omicron variant during pregnancy was not statistically significant correlated with common infant illnesses in infancy and neurodevelopment at age one.http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2025.24128?viewType=HTMLperiod of pregnancysars-cov-2 omicron variantcommon illnesses in infantsneural development
spellingShingle XU Weiqing
LUO Dan
JIANG Hong
SHI Junyao
Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants
Shanghai yufang yixue
period of pregnancy
sars-cov-2 omicron variant
common illnesses in infants
neural development
title Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants
title_full Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants
title_fullStr Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants
title_full_unstemmed Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants
title_short Analysis of association between infection with SARS-CoV-2 Omicron variant during pregnancy and common illnesses of infants
title_sort analysis of association between infection with sars cov 2 omicron variant during pregnancy and common illnesses of infants
topic period of pregnancy
sars-cov-2 omicron variant
common illnesses in infants
neural development
url http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2025.24128?viewType=HTML
work_keys_str_mv AT xuweiqing analysisofassociationbetweeninfectionwithsarscov2omicronvariantduringpregnancyandcommonillnessesofinfants
AT luodan analysisofassociationbetweeninfectionwithsarscov2omicronvariantduringpregnancyandcommonillnessesofinfants
AT jianghong analysisofassociationbetweeninfectionwithsarscov2omicronvariantduringpregnancyandcommonillnessesofinfants
AT shijunyao analysisofassociationbetweeninfectionwithsarscov2omicronvariantduringpregnancyandcommonillnessesofinfants