The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries

Campylobacter spp., primarily C. jejuni and C. coli, are leading causes of bacterial gastroenteritis worldwide. This review provides an overview of literature on the prevalence and distribution of virulence genes in C. jejuni and C. coli isolated from both food samples and humans across GCC countrie...

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Main Authors: Mohamed-Yousif Ibrahim Mohamed, Hazim O. Khalifa, Ihab Habib
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1584835/full
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author Mohamed-Yousif Ibrahim Mohamed
Mohamed-Yousif Ibrahim Mohamed
Hazim O. Khalifa
Ihab Habib
Ihab Habib
author_facet Mohamed-Yousif Ibrahim Mohamed
Mohamed-Yousif Ibrahim Mohamed
Hazim O. Khalifa
Ihab Habib
Ihab Habib
author_sort Mohamed-Yousif Ibrahim Mohamed
collection DOAJ
description Campylobacter spp., primarily C. jejuni and C. coli, are leading causes of bacterial gastroenteritis worldwide. This review provides an overview of literature on the prevalence and distribution of virulence genes in C. jejuni and C. coli isolated from both food samples and humans across GCC countries. The reviewed evidence highlights a gap in our understanding of how differences in the virulence profile affect the pathogenicity of Campylobacter. Research has shown that C. coli is the predominant species found in retail chicken carcasses in the UAE, while C. jejuni is more common in chicken carcasses across other GCC countries. Studies also reveal distinct genotypes of C. jejuni and C. coli, each with varying pathogenicity. These findings underscore the need for further research on the role of virulence genes in shaping the pathogenicity of Campylobacter, which is essential for developing effective intervention and control strategies in the GCC region.
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spelling doaj-art-9def7ea8fa9e48f9bcb5c57cc172b7ef2025-08-20T02:18:36ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882025-04-011510.3389/fcimb.2025.15848351584835The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countriesMohamed-Yousif Ibrahim Mohamed0Mohamed-Yousif Ibrahim Mohamed1Hazim O. Khalifa2Ihab Habib3Ihab Habib4Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab of Emirates University, Al Ain, United Arab EmiratesASPIRE Research Institute for Food Security in the Drylands (ARIFSID), United Arab Emirates University, Al Ain, United Arab EmiratesDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab of Emirates University, Al Ain, United Arab EmiratesDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab of Emirates University, Al Ain, United Arab EmiratesASPIRE Research Institute for Food Security in the Drylands (ARIFSID), United Arab Emirates University, Al Ain, United Arab EmiratesCampylobacter spp., primarily C. jejuni and C. coli, are leading causes of bacterial gastroenteritis worldwide. This review provides an overview of literature on the prevalence and distribution of virulence genes in C. jejuni and C. coli isolated from both food samples and humans across GCC countries. The reviewed evidence highlights a gap in our understanding of how differences in the virulence profile affect the pathogenicity of Campylobacter. Research has shown that C. coli is the predominant species found in retail chicken carcasses in the UAE, while C. jejuni is more common in chicken carcasses across other GCC countries. Studies also reveal distinct genotypes of C. jejuni and C. coli, each with varying pathogenicity. These findings underscore the need for further research on the role of virulence genes in shaping the pathogenicity of Campylobacter, which is essential for developing effective intervention and control strategies in the GCC region.https://www.frontiersin.org/articles/10.3389/fcimb.2025.1584835/fullCampylobactervirulence genesfoodborne infectionone healthGulf Cooperation Council countries
spellingShingle Mohamed-Yousif Ibrahim Mohamed
Mohamed-Yousif Ibrahim Mohamed
Hazim O. Khalifa
Ihab Habib
Ihab Habib
The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries
Frontiers in Cellular and Infection Microbiology
Campylobacter
virulence genes
foodborne infection
one health
Gulf Cooperation Council countries
title The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries
title_full The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries
title_fullStr The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries
title_full_unstemmed The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries
title_short The role of virulence genes in Campylobacter pathogenicity: a perspective from the Gulf Cooperation Council countries
title_sort role of virulence genes in campylobacter pathogenicity a perspective from the gulf cooperation council countries
topic Campylobacter
virulence genes
foodborne infection
one health
Gulf Cooperation Council countries
url https://www.frontiersin.org/articles/10.3389/fcimb.2025.1584835/full
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