Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted i...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2021/6633217 |
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| _version_ | 1832550089849044992 |
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| author | S. Choayb H. Adil Daoud Ali Mohamed N. Allali L. Chat S. El Haddad |
| author_facet | S. Choayb H. Adil Daoud Ali Mohamed N. Allali L. Chat S. El Haddad |
| author_sort | S. Choayb |
| collection | DOAJ |
| description | Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted images showed the classic eye of the tiger sign seen in pantothenate kinase-associated neurodegeneration. |
| format | Article |
| id | doaj-art-9dec0ab840b9478da4df65a67ff13e13 |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-9dec0ab840b9478da4df65a67ff13e132025-02-03T06:07:40ZengWileyCase Reports in Radiology2090-68622090-68702021-01-01202110.1155/2021/66332176633217Eye of the Tiger Sign in Pantothenate Kinase-Associated NeurodegenerationS. Choayb0H. Adil1Daoud Ali Mohamed2N. Allali3L. Chat4S. El Haddad5Children’s Hospital, Radiology Department, Mohamed V University, Rabat, MoroccoChildren’s Hospital, Radiology Department, Mohamed V University, Rabat, MoroccoChildren’s Hospital, Radiology Department, Mohamed V University, Rabat, MoroccoChildren’s Hospital, Radiology Department, Mohamed V University, Rabat, MoroccoChildren’s Hospital, Radiology Department, Mohamed V University, Rabat, MoroccoChildren’s Hospital, Radiology Department, Mohamed V University, Rabat, MoroccoPantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted images showed the classic eye of the tiger sign seen in pantothenate kinase-associated neurodegeneration.http://dx.doi.org/10.1155/2021/6633217 |
| spellingShingle | S. Choayb H. Adil Daoud Ali Mohamed N. Allali L. Chat S. El Haddad Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration Case Reports in Radiology |
| title | Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration |
| title_full | Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration |
| title_fullStr | Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration |
| title_full_unstemmed | Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration |
| title_short | Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration |
| title_sort | eye of the tiger sign in pantothenate kinase associated neurodegeneration |
| url | http://dx.doi.org/10.1155/2021/6633217 |
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