HSF1 is essential for the resistance of zebrafish eye and brain tissues to hypoxia/reperfusion injury.
Ischemia and subsequent reperfusion (IR) produces injury to brain, eye and other tissues, contributing to the progression of important clinical pathologies. The response of cells to IR involves activation of several signaling pathways including those activating hypoxia and heat shock responsive tran...
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| Main Authors: | Nathan R Tucker, Ryan C Middleton, Quynh P Le, Eric A Shelden |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022268&type=printable |
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