Evaluation of chimeric antigen receptor T cell therapy in non-human primates infected with SHIV or SIV.

Evaluation of chimeric antigen receptor T cell therapy in non-human primates infected with SHIV or SIV.

Achieving a functional cure is an important goal in the development of HIV therapy. Eliciting HIV-specific cellular immune responses has not been sufficient to achieve durable removal of HIV-infected cells due to the restriction on effective immune responses by mutation and establishment of latent r...

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Bibliographic Details
Main Authors: Nami Iwamoto, Bhavik Patel, Kaimei Song, Rosemarie Mason, Sara Bolivar-Wagers, Cristina Bergamaschi, George N Pavlakis, Edward Berger, Mario Roederer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0248973&type=printable
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