Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood
Aim. To analyze efficacy of levetiracetam monotherapy in patients with epilepsy associated with benign epileptiform discharges of childhood (BEDC). Materials and methods. We examined 29 pediatric patients with idiopathic and symptomatic BEDC-associated epilepsy, including continuous spike-and-wave e...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2019-04-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/458 |
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| author | N. A. Borovkova A. G. Malov |
| author_facet | N. A. Borovkova A. G. Malov |
| author_sort | N. A. Borovkova |
| collection | DOAJ |
| description | Aim. To analyze efficacy of levetiracetam monotherapy in patients with epilepsy associated with benign epileptiform discharges of childhood (BEDC). Materials and methods. We examined 29 pediatric patients with idiopathic and symptomatic BEDC-associated epilepsy, including continuous spike-and-wave epileptiform activity during slow-wave sleep (CSWS) in the stage of clinical remission. Of those, 12 children received antiepileptic treatment with valproic acid, and 17 children received levetiracetam. The examination included passive awake EEG recordings (with functional tests) as well as daytime sleep EEG recordings (within 60 minutes). Results. Levetiracetam was no less efficient in monotherapy of BEDC-associated epilepsy (including the CSWS patterns) than the traditionally used valproic acid, especially in idiopathic forms of epilepsy. Conclusion. Levetiracetam can be recommended for the first-choice basic anti-epileptic monotherapy treatment. |
| format | Article |
| id | doaj-art-9dc8e4955eec479eb7d837fa3f96f445 |
| institution | Kabale University |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| publishDate | 2019-04-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj-art-9dc8e4955eec479eb7d837fa3f96f4452025-08-20T03:57:32ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882019-04-01111636810.17749/2077-8333.2019.11.1.63-68434Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhoodN. A. Borovkova0A. G. Malov1Children’s Clinical Hospital named after P. I. PichuginVagner Perm State Medical UniversityAim. To analyze efficacy of levetiracetam monotherapy in patients with epilepsy associated with benign epileptiform discharges of childhood (BEDC). Materials and methods. We examined 29 pediatric patients with idiopathic and symptomatic BEDC-associated epilepsy, including continuous spike-and-wave epileptiform activity during slow-wave sleep (CSWS) in the stage of clinical remission. Of those, 12 children received antiepileptic treatment with valproic acid, and 17 children received levetiracetam. The examination included passive awake EEG recordings (with functional tests) as well as daytime sleep EEG recordings (within 60 minutes). Results. Levetiracetam was no less efficient in monotherapy of BEDC-associated epilepsy (including the CSWS patterns) than the traditionally used valproic acid, especially in idiopathic forms of epilepsy. Conclusion. Levetiracetam can be recommended for the first-choice basic anti-epileptic monotherapy treatment.https://www.epilepsia.su/jour/article/view/458epilepsybenign epileptiform discharges of childhoodcontinuous spike-and-wave epileptiform activitylevetiracetam |
| spellingShingle | N. A. Borovkova A. G. Malov Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood Эпилепсия и пароксизмальные состояния epilepsy benign epileptiform discharges of childhood continuous spike-and-wave epileptiform activity levetiracetam |
| title | Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood |
| title_full | Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood |
| title_fullStr | Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood |
| title_full_unstemmed | Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood |
| title_short | Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood |
| title_sort | efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood |
| topic | epilepsy benign epileptiform discharges of childhood continuous spike-and-wave epileptiform activity levetiracetam |
| url | https://www.epilepsia.su/jour/article/view/458 |
| work_keys_str_mv | AT naborovkova efficacyoflevetiracetammonotherapyinepilepsyassociatedwithbenignepileptiformdischargesofchildhood AT agmalov efficacyoflevetiracetammonotherapyinepilepsyassociatedwithbenignepileptiformdischargesofchildhood |