Intraductal chemotherapy for triple-negative breast cancer: a pathway to minimally invasive clinical treatment

Intraductal chemotherapy for triple-negative breast cancer: a pathway to minimally invasive clinical treatment

Abstract Triple-negative breast cancer (TNBC) is traditionally treated with systemic chemotherapy, often resulting in significant off-target toxicity. In this study, we assess the efficacy of intraductal chemotherapeutic delivery, aimed at reducing systemic side effects. Using an in situ TNBC model,...

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Bibliographic Details
Main Authors: Xinhong Wu, Feng Yuan, Liantao Guo, Dongcheng Gao, Weijie Zheng, Chuang Chen, Hongmei Zheng, Jianhua Liu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Triple-negative breast cancer
Intraductal therapy
Epithelial-mesenchymal transition
Minimally invasive treatment
Chemo-immunomodulation
Online Access:https://doi.org/10.1186/s12885-025-13693-0
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