Potential of nutraceutical products for irritable bowel syndrome remission maintenance
Aim of review. To summarize the modern data on pathogenesis of symptoms irritable bowel syndrome (IBS) symptoms, to present nutraceutical product «Standart zdorovya: GASTRO» as an agent for IBS remission maintenance. Summary. Recent data indicate essential changes of intestinal microbiota in IBS in...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2018-08-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/233 |
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| author | A. I. Ulyanin Ye. A. Poluektova Ch. S. Pavlov V. T. Ivashkin |
| author_facet | A. I. Ulyanin Ye. A. Poluektova Ch. S. Pavlov V. T. Ivashkin |
| author_sort | A. I. Ulyanin |
| collection | DOAJ |
| description | Aim of review. To summarize the modern data on pathogenesis of symptoms irritable bowel syndrome (IBS) symptoms, to present nutraceutical product «Standart zdorovya: GASTRO» as an agent for IBS remission maintenance. Summary. Recent data indicate essential changes of intestinal microbiota in IBS in comparison to healthy population. These changes may be associated to development of inflammatory processes of intestinal wall. Long-term inflammation may result in nociceptor hypersensitivity i.e. peripheral sensitization that in turn, lead to the central sensitization and indirectly - to gastrointestinal tract (GIT) motility disorders. Besides, change of intestinal microbiota may impact the development of emotional disorders (e.g.: impaired capacity of affected intestinal microbiota to produce neurotransmitters). Therefore, according to the results of available studies, intestinal microbiota changes in IBS is a key factor for the cascade of events including intestinal wall inflammation, changes of gastrointestinal motility, decreased threshold of gastrointestinal receptor sensitivity, as well as emotional disorders resulting in development of disease symptoms. Medical preparation for IBS remission induction and remission maintenance should possess probiotic/prebiotic and anti-inflammatory properties, reduce visceral sensitivity, normalize intestinal motility and modulate patients’ emotional sphere. Due to capacity of «Standart zdorovya: GASTRO» components to deliver above-listed effects it can be promising for administration in patients with IBS. |
| format | Article |
| id | doaj-art-9dc50db1d4d742bcb47dd25c4b35320d |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2018-08-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-9dc50db1d4d742bcb47dd25c4b35320d2025-02-10T16:14:28ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732018-08-0128210110810.22416/1382-4376-2018-28-2-101-108233Potential of nutraceutical products for irritable bowel syndrome remission maintenanceA. I. Ulyanin0Ye. A. Poluektova1Ch. S. Pavlov2V. T. Ivashkin3Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Aim of review. To summarize the modern data on pathogenesis of symptoms irritable bowel syndrome (IBS) symptoms, to present nutraceutical product «Standart zdorovya: GASTRO» as an agent for IBS remission maintenance. Summary. Recent data indicate essential changes of intestinal microbiota in IBS in comparison to healthy population. These changes may be associated to development of inflammatory processes of intestinal wall. Long-term inflammation may result in nociceptor hypersensitivity i.e. peripheral sensitization that in turn, lead to the central sensitization and indirectly - to gastrointestinal tract (GIT) motility disorders. Besides, change of intestinal microbiota may impact the development of emotional disorders (e.g.: impaired capacity of affected intestinal microbiota to produce neurotransmitters). Therefore, according to the results of available studies, intestinal microbiota changes in IBS is a key factor for the cascade of events including intestinal wall inflammation, changes of gastrointestinal motility, decreased threshold of gastrointestinal receptor sensitivity, as well as emotional disorders resulting in development of disease symptoms. Medical preparation for IBS remission induction and remission maintenance should possess probiotic/prebiotic and anti-inflammatory properties, reduce visceral sensitivity, normalize intestinal motility and modulate patients’ emotional sphere. Due to capacity of «Standart zdorovya: GASTRO» components to deliver above-listed effects it can be promising for administration in patients with IBS.https://www.gastro-j.ru/jour/article/view/233синдром раздраженного кишечниканутрицевтические продуктымикробиотаремиссия |
| spellingShingle | A. I. Ulyanin Ye. A. Poluektova Ch. S. Pavlov V. T. Ivashkin Potential of nutraceutical products for irritable bowel syndrome remission maintenance Российский журнал гастроэнтерологии, гепатологии, колопроктологии синдром раздраженного кишечника нутрицевтические продукты микробиота ремиссия |
| title | Potential of nutraceutical products for irritable bowel syndrome remission maintenance |
| title_full | Potential of nutraceutical products for irritable bowel syndrome remission maintenance |
| title_fullStr | Potential of nutraceutical products for irritable bowel syndrome remission maintenance |
| title_full_unstemmed | Potential of nutraceutical products for irritable bowel syndrome remission maintenance |
| title_short | Potential of nutraceutical products for irritable bowel syndrome remission maintenance |
| title_sort | potential of nutraceutical products for irritable bowel syndrome remission maintenance |
| topic | синдром раздраженного кишечника нутрицевтические продукты микробиота ремиссия |
| url | https://www.gastro-j.ru/jour/article/view/233 |
| work_keys_str_mv | AT aiulyanin potentialofnutraceuticalproductsforirritablebowelsyndromeremissionmaintenance AT yeapoluektova potentialofnutraceuticalproductsforirritablebowelsyndromeremissionmaintenance AT chspavlov potentialofnutraceuticalproductsforirritablebowelsyndromeremissionmaintenance AT vtivashkin potentialofnutraceuticalproductsforirritablebowelsyndromeremissionmaintenance |