APOE genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia

Abstract Objective Recent work has bolstered the possibility that peripheral changes may be relevant to Alzheimer's disease pathogenesis in the brain. While age‐associated blood‐borne proteins have been targeted to restore function to the aged brain, it remains unclear whether other dysfunction...

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Bibliographic Details
Main Authors: Sarah M. Philippi, Kailash BP, Towfique Raj, Joseph M. Castellano
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.52250
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