Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications
Hydrogel is one of the most prominent biomaterials in therapeutic and biomedical engineering, benefiting from its biocompatibility, chemical/physical tunability, and wide versatility to various fabrication techniques. One remarkable advance in the latest hydrogel research is the micro/nanofabricatio...
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| Format: | Article |
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MDPI AG
2025-01-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/15/3/1368 |
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| author | Yuri Choi Hye Yeon Koh Jung Y. Han Soonmin Seo |
| author_facet | Yuri Choi Hye Yeon Koh Jung Y. Han Soonmin Seo |
| author_sort | Yuri Choi |
| collection | DOAJ |
| description | Hydrogel is one of the most prominent biomaterials in therapeutic and biomedical engineering, benefiting from its biocompatibility, chemical/physical tunability, and wide versatility to various fabrication techniques. One remarkable advance in the latest hydrogel research is the micro/nanofabrication technologies, which utilize unique mechanical and chemical properties of hydrogel, various chemical reaction mechanisms, and multidisciplinary approaches to realize innovative systems at these size scales. This review reports a comprehensive overview on the latest advances in fabrication of hydrogel-based micro- and nano-systems with an emphasis on their biomedical and therapeutic applications. Challenges and prospects are discussed from the material, fabrication, and system design perspectives to develop effective, personalized, and versatile hydrogel-based therapies. |
| format | Article |
| id | doaj-art-9db3d4f8204147918b09d56fb1f69e23 |
| institution | DOAJ |
| issn | 2076-3417 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj-art-9db3d4f8204147918b09d56fb1f69e232025-08-20T02:48:06ZengMDPI AGApplied Sciences2076-34172025-01-01153136810.3390/app15031368Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical ApplicationsYuri Choi0Hye Yeon Koh1Jung Y. Han2Soonmin Seo3Department of Bionanotechnology, Gachon University, Seongnam 13120, Republic of KoreaDepartment of Bionanotechnology, Gachon University, Seongnam 13120, Republic of KoreaDepartment of Bionanotechnology, Gachon University, Seongnam 13120, Republic of KoreaDepartment of Bionanotechnology, Gachon University, Seongnam 13120, Republic of KoreaHydrogel is one of the most prominent biomaterials in therapeutic and biomedical engineering, benefiting from its biocompatibility, chemical/physical tunability, and wide versatility to various fabrication techniques. One remarkable advance in the latest hydrogel research is the micro/nanofabrication technologies, which utilize unique mechanical and chemical properties of hydrogel, various chemical reaction mechanisms, and multidisciplinary approaches to realize innovative systems at these size scales. This review reports a comprehensive overview on the latest advances in fabrication of hydrogel-based micro- and nano-systems with an emphasis on their biomedical and therapeutic applications. Challenges and prospects are discussed from the material, fabrication, and system design perspectives to develop effective, personalized, and versatile hydrogel-based therapies.https://www.mdpi.com/2076-3417/15/3/1368hydrogelnanogelsmicrogelsdrug delivery systemscontrolled synthesismicrofluidic synthesis |
| spellingShingle | Yuri Choi Hye Yeon Koh Jung Y. Han Soonmin Seo Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications Applied Sciences hydrogel nanogels microgels drug delivery systems controlled synthesis microfluidic synthesis |
| title | Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications |
| title_full | Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications |
| title_fullStr | Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications |
| title_full_unstemmed | Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications |
| title_short | Synthesis of Hydrogel-Based Microgels and Nanogels Toward Therapeutic and Biomedical Applications |
| title_sort | synthesis of hydrogel based microgels and nanogels toward therapeutic and biomedical applications |
| topic | hydrogel nanogels microgels drug delivery systems controlled synthesis microfluidic synthesis |
| url | https://www.mdpi.com/2076-3417/15/3/1368 |
| work_keys_str_mv | AT yurichoi synthesisofhydrogelbasedmicrogelsandnanogelstowardtherapeuticandbiomedicalapplications AT hyeyeonkoh synthesisofhydrogelbasedmicrogelsandnanogelstowardtherapeuticandbiomedicalapplications AT jungyhan synthesisofhydrogelbasedmicrogelsandnanogelstowardtherapeuticandbiomedicalapplications AT soonminseo synthesisofhydrogelbasedmicrogelsandnanogelstowardtherapeuticandbiomedicalapplications |