Magnetic resonance thermometry for hyperthermia in the oropharynx region
Magnetic resonance thermometry (MRT) can measure in-vivo 3D-temperature changes in real-time and noninvasively. However, for the oropharynx region and the entire head and neck, motion potentially introduces large artifacts. Considering long treatment times of 60–90 min, this study aims to evaluate w...
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| Format: | Article |
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2024.2352545 |
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| author | Theresa V. Feddersen Juan A. Hernandez-Tamames Margarethus M. Paulides Michiel Kroesen Gerard C. van Rhoon Dirk H.J Poot |
| author_facet | Theresa V. Feddersen Juan A. Hernandez-Tamames Margarethus M. Paulides Michiel Kroesen Gerard C. van Rhoon Dirk H.J Poot |
| author_sort | Theresa V. Feddersen |
| collection | DOAJ |
| description | Magnetic resonance thermometry (MRT) can measure in-vivo 3D-temperature changes in real-time and noninvasively. However, for the oropharynx region and the entire head and neck, motion potentially introduces large artifacts. Considering long treatment times of 60–90 min, this study aims to evaluate whether MRT around the oropharynx is clinically feasible for hyperthermia treatments and quantify the effects of breathing and swallowing on MRT performance. A 3D-ME-FGRE sequence was used in a phantom cooling down and around the oropharynx of five volunteers over ∼75 min. The imaging protocol consisted of imaging with acceleration (ARC = 2), number of image averages (NEX = 1,2 and 3). For volunteers, the acquisitions included a breath-hold scan and scans with deliberate swallowing. MRT performance was quantified in neck muscle, spinal cord and masseter muscle, using mean average error (MAE), mean error (ME) and spatial standard deviation (SD). In phantom, an increase in NEX leads to a significant decrease in SD, but MAE and ME were unchanged. No significant difference was found in volunteers between the different scans. There was a significant difference between the regions evaluated: neck muscle had the best MAE (=1.96 °C) and SD (=0.82 °C), followed by spinal cord (MAE = 3.17 °C, SD = 0.92 °C) and masseter muscle (MAE = 4.53 °C, SD = 1.16 °C). Concerning the ME, spinal cord did best, then neck muscle and masseter muscle, with values of −0.64 °C, 1.15 °C and −3.05 °C respectively. Breathing, swallowing, and different ways of imaging (acceleration and NEX) do not significantly influence the MRT performance in the oropharynx region. The ROI selected however, leads to significant differences. |
| format | Article |
| id | doaj-art-9dafe38efd2549bfb0f2a019ac47980d |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-9dafe38efd2549bfb0f2a019ac47980d2025-01-03T09:30:27ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2024.2352545Magnetic resonance thermometry for hyperthermia in the oropharynx regionTheresa V. Feddersen0Juan A. Hernandez-Tamames1Margarethus M. Paulides2Michiel Kroesen3Gerard C. van Rhoon4Dirk H.J Poot5Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the NetherlandsDepartment of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the NetherlandsDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the NetherlandsDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the NetherlandsDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the NetherlandsDepartment of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the NetherlandsMagnetic resonance thermometry (MRT) can measure in-vivo 3D-temperature changes in real-time and noninvasively. However, for the oropharynx region and the entire head and neck, motion potentially introduces large artifacts. Considering long treatment times of 60–90 min, this study aims to evaluate whether MRT around the oropharynx is clinically feasible for hyperthermia treatments and quantify the effects of breathing and swallowing on MRT performance. A 3D-ME-FGRE sequence was used in a phantom cooling down and around the oropharynx of five volunteers over ∼75 min. The imaging protocol consisted of imaging with acceleration (ARC = 2), number of image averages (NEX = 1,2 and 3). For volunteers, the acquisitions included a breath-hold scan and scans with deliberate swallowing. MRT performance was quantified in neck muscle, spinal cord and masseter muscle, using mean average error (MAE), mean error (ME) and spatial standard deviation (SD). In phantom, an increase in NEX leads to a significant decrease in SD, but MAE and ME were unchanged. No significant difference was found in volunteers between the different scans. There was a significant difference between the regions evaluated: neck muscle had the best MAE (=1.96 °C) and SD (=0.82 °C), followed by spinal cord (MAE = 3.17 °C, SD = 0.92 °C) and masseter muscle (MAE = 4.53 °C, SD = 1.16 °C). Concerning the ME, spinal cord did best, then neck muscle and masseter muscle, with values of −0.64 °C, 1.15 °C and −3.05 °C respectively. Breathing, swallowing, and different ways of imaging (acceleration and NEX) do not significantly influence the MRT performance in the oropharynx region. The ROI selected however, leads to significant differences.https://www.tandfonline.com/doi/10.1080/02656736.2024.2352545Magnetic resonance thermometryMRThead and neckhyperthermiaPRFS |
| spellingShingle | Theresa V. Feddersen Juan A. Hernandez-Tamames Margarethus M. Paulides Michiel Kroesen Gerard C. van Rhoon Dirk H.J Poot Magnetic resonance thermometry for hyperthermia in the oropharynx region International Journal of Hyperthermia Magnetic resonance thermometry MRT head and neck hyperthermia PRFS |
| title | Magnetic resonance thermometry for hyperthermia in the oropharynx region |
| title_full | Magnetic resonance thermometry for hyperthermia in the oropharynx region |
| title_fullStr | Magnetic resonance thermometry for hyperthermia in the oropharynx region |
| title_full_unstemmed | Magnetic resonance thermometry for hyperthermia in the oropharynx region |
| title_short | Magnetic resonance thermometry for hyperthermia in the oropharynx region |
| title_sort | magnetic resonance thermometry for hyperthermia in the oropharynx region |
| topic | Magnetic resonance thermometry MRT head and neck hyperthermia PRFS |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2024.2352545 |
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