Surgical Approaches to Chronic Pancreatitis

Chronic pancreatitis is a progressive inflammatory disease resulting in permanent structural damage of the pancreas. It is mainly characterized by recurring epigastric pain and pancreatic insufficiency. In addition, progression of the disease might lead to additional complications, such as pseudocys...

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Main Authors: Daniel Hartmann, Helmut Friess
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/503109
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author Daniel Hartmann
Helmut Friess
author_facet Daniel Hartmann
Helmut Friess
author_sort Daniel Hartmann
collection DOAJ
description Chronic pancreatitis is a progressive inflammatory disease resulting in permanent structural damage of the pancreas. It is mainly characterized by recurring epigastric pain and pancreatic insufficiency. In addition, progression of the disease might lead to additional complications, such as pseudocyst formation or development of pancreatic cancer. The medical and surgical treatment of chronic pancreatitis has changed significantly in the past decades. With regard to surgical management, pancreatic head resection has been shown to be a mainstay in the treatment of severe chronic pancreatitis because the pancreatic head mass is known to trigger the chronic inflammatory process. Over the years, organ-preserving procedures, such as the duodenum-preserving pancreatic head resection and the pylorus-preserving Whipple, have become the surgical standard and have led to major improvements in pain relief, preservation of pancreatic function, and quality of life of patients.
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spelling doaj-art-9daf065ea60442b0ae428d31c7086af62025-08-20T02:20:30ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/503109503109Surgical Approaches to Chronic PancreatitisDaniel Hartmann0Helmut Friess1Department of Surgery, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, GermanyDepartment of Surgery, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 Munich, GermanyChronic pancreatitis is a progressive inflammatory disease resulting in permanent structural damage of the pancreas. It is mainly characterized by recurring epigastric pain and pancreatic insufficiency. In addition, progression of the disease might lead to additional complications, such as pseudocyst formation or development of pancreatic cancer. The medical and surgical treatment of chronic pancreatitis has changed significantly in the past decades. With regard to surgical management, pancreatic head resection has been shown to be a mainstay in the treatment of severe chronic pancreatitis because the pancreatic head mass is known to trigger the chronic inflammatory process. Over the years, organ-preserving procedures, such as the duodenum-preserving pancreatic head resection and the pylorus-preserving Whipple, have become the surgical standard and have led to major improvements in pain relief, preservation of pancreatic function, and quality of life of patients.http://dx.doi.org/10.1155/2015/503109
spellingShingle Daniel Hartmann
Helmut Friess
Surgical Approaches to Chronic Pancreatitis
Gastroenterology Research and Practice
title Surgical Approaches to Chronic Pancreatitis
title_full Surgical Approaches to Chronic Pancreatitis
title_fullStr Surgical Approaches to Chronic Pancreatitis
title_full_unstemmed Surgical Approaches to Chronic Pancreatitis
title_short Surgical Approaches to Chronic Pancreatitis
title_sort surgical approaches to chronic pancreatitis
url http://dx.doi.org/10.1155/2015/503109
work_keys_str_mv AT danielhartmann surgicalapproachestochronicpancreatitis
AT helmutfriess surgicalapproachestochronicpancreatitis