MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES
Mitochondria import hundreds of different precursor proteins from the cytosol, and only 13 proteins are encoded by mtDNA itself. Recent investigations demonstrated real size of mitochondrial proteome and complexity of their functions There are many methods using for mitochondrial proteome profiling,...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2013-06-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/333 |
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| author | Ye. A. Kosterina I. I. Kozenkov V. A. Kasymov P. A. Kamensky I. N. Dominova Yu. A. Korolyova V. Ye. Patrusheva R. S. Bogachev L. S. Litvinova S. V. Babak Ye. M. Moiseeva Ye. A. Bogdanov O. A. Mukhortova Ya. S. Vavilina T. A. Mikhalchenkova M. V. Patrushev |
| author_facet | Ye. A. Kosterina I. I. Kozenkov V. A. Kasymov P. A. Kamensky I. N. Dominova Yu. A. Korolyova V. Ye. Patrusheva R. S. Bogachev L. S. Litvinova S. V. Babak Ye. M. Moiseeva Ye. A. Bogdanov O. A. Mukhortova Ya. S. Vavilina T. A. Mikhalchenkova M. V. Patrushev |
| author_sort | Ye. A. Kosterina |
| collection | DOAJ |
| description | Mitochondria import hundreds of different precursor proteins from the cytosol, and only 13 proteins are encoded by mtDNA itself. Recent investigations demonstrated real size of mitochondrial proteome and complexity of their functions There are many methods using for mitochondrial proteome profiling, that help to understand a molecular mechanisms of mitochondrial functions and identify the causes of disruptions that lead to different disorders. In this review we discuss a recent data in the field of mitochondrial proteomics. |
| format | Article |
| id | doaj-art-9d95f1aa398245579d65276b2e866639 |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2013-06-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-9d95f1aa398245579d65276b2e8666392025-08-20T03:21:43ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842013-06-0112351710.20538/1682-0363-2013-3-5-17329MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSESYe. A. Kosterina0I. I. Kozenkov1V. A. Kasymov2P. A. Kamensky3I. N. Dominova4Yu. A. Korolyova5V. Ye. Patrusheva6R. S. Bogachev7L. S. Litvinova8S. V. Babak9Ye. M. Moiseeva10Ye. A. Bogdanov11O. A. Mukhortova12Ya. S. Vavilina13T. A. Mikhalchenkova14M. V. Patrushev15Immanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradImmanuel Kant Baltic Federal University, KaliningradMitochondria import hundreds of different precursor proteins from the cytosol, and only 13 proteins are encoded by mtDNA itself. Recent investigations demonstrated real size of mitochondrial proteome and complexity of their functions There are many methods using for mitochondrial proteome profiling, that help to understand a molecular mechanisms of mitochondrial functions and identify the causes of disruptions that lead to different disorders. In this review we discuss a recent data in the field of mitochondrial proteomics.https://bulletin.ssmu.ru/jour/article/view/333mitochondrial proteomeprotein importrespiratory chain proteinsmitochondrial dnarespiratory chain disorders |
| spellingShingle | Ye. A. Kosterina I. I. Kozenkov V. A. Kasymov P. A. Kamensky I. N. Dominova Yu. A. Korolyova V. Ye. Patrusheva R. S. Bogachev L. S. Litvinova S. V. Babak Ye. M. Moiseeva Ye. A. Bogdanov O. A. Mukhortova Ya. S. Vavilina T. A. Mikhalchenkova M. V. Patrushev MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES Бюллетень сибирской медицины mitochondrial proteome protein import respiratory chain proteins mitochondrial dna respiratory chain disorders |
| title | MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES |
| title_full | MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES |
| title_fullStr | MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES |
| title_full_unstemmed | MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES |
| title_short | MITOCHONDRIAL PROTEIN PROFILE AND ITS ROLE IN PATHOLOGIC PROCESSES |
| title_sort | mitochondrial protein profile and its role in pathologic processes |
| topic | mitochondrial proteome protein import respiratory chain proteins mitochondrial dna respiratory chain disorders |
| url | https://bulletin.ssmu.ru/jour/article/view/333 |
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