Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy

A patient who developed an atypical manifestation of Mycobacterium avium complex (MAC) infection almost two years after starting effective highly active antiretroviral therapy is described. The recurrence, manifested as brain abscesses in the central nervous system, was an uncommon form of MAC...

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Main Authors: Claude Fortin, Danielle Rouleau
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2005/524091
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author Claude Fortin
Danielle Rouleau
author_facet Claude Fortin
Danielle Rouleau
author_sort Claude Fortin
collection DOAJ
description A patient who developed an atypical manifestation of Mycobacterium avium complex (MAC) infection almost two years after starting effective highly active antiretroviral therapy is described. The recurrence, manifested as brain abscesses in the central nervous system, was an uncommon form of MAC disease usually reported postmortem. An increased CD4 cell count, localized and suppurative infection, and the absence of systemic evidence of infection were consistent with a late immune reconstitution syndrome. The present case report adds to the understanding of MAC disease in HIV-infected patients.
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spelling doaj-art-9d90e280cd864c9caa25d4a0bce9304e2025-02-03T05:49:46ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322005-01-0116318718910.1155/2005/524091Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapyClaude Fortin0Danielle RouleauDépartement de Microbiologie médicale et Infectiologie, Centre Hospitalier de l’Université de Montréal, Université de Montréal, Montréal, Québec, CanadaA patient who developed an atypical manifestation of Mycobacterium avium complex (MAC) infection almost two years after starting effective highly active antiretroviral therapy is described. The recurrence, manifested as brain abscesses in the central nervous system, was an uncommon form of MAC disease usually reported postmortem. An increased CD4 cell count, localized and suppurative infection, and the absence of systemic evidence of infection were consistent with a late immune reconstitution syndrome. The present case report adds to the understanding of MAC disease in HIV-infected patients.http://dx.doi.org/10.1155/2005/524091
spellingShingle Claude Fortin
Danielle Rouleau
Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
Canadian Journal of Infectious Diseases and Medical Microbiology
title Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
title_full Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
title_fullStr Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
title_full_unstemmed Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
title_short Cerebral Mycobacterium avium abscesses: Late immune reconstitution syndrome in an HIV-1-infected patient receiving highly active antiretroviral therapy
title_sort cerebral mycobacterium avium abscesses late immune reconstitution syndrome in an hiv 1 infected patient receiving highly active antiretroviral therapy
url http://dx.doi.org/10.1155/2005/524091
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AT daniellerouleau cerebralmycobacteriumaviumabscesseslateimmunereconstitutionsyndromeinanhiv1infectedpatientreceivinghighlyactiveantiretroviraltherapy