Adult nephroblastoma or Wilms' tumor: A rare entity - Case report

Wilms' tumor (nephroblastoma) is rare in adults, comprising less than 5 % of renal cancers. This report details a 48-year-old male with persistent abdominal pain, weight loss, and fatigue, whose imaging showed a large, heterogeneous left renal mass with regional lymph node involvement. Post-nep...

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Main Authors: Salim Lachkar, Ahmed Ibrahimi, Imad Boualaoui, Hachem El Sayegh, Yassine Nouini
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Urology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214442024002122
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author Salim Lachkar
Ahmed Ibrahimi
Imad Boualaoui
Hachem El Sayegh
Yassine Nouini
author_facet Salim Lachkar
Ahmed Ibrahimi
Imad Boualaoui
Hachem El Sayegh
Yassine Nouini
author_sort Salim Lachkar
collection DOAJ
description Wilms' tumor (nephroblastoma) is rare in adults, comprising less than 5 % of renal cancers. This report details a 48-year-old male with persistent abdominal pain, weight loss, and fatigue, whose imaging showed a large, heterogeneous left renal mass with regional lymph node involvement. Post-nephrectomy histology confirmed nephroblastoma with a triphasic pattern. The patient underwent left radical nephrectomy and received adjuvant chemotherapy with doxorubicin, vincristine, and actinomycin D. Three months later, follow-up CT scans revealed no residual disease. This case underscores the diagnostic and therapeutic challenges of adult nephroblastoma and the need for more effective treatment protocols.
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series Urology Case Reports
spelling doaj-art-9d8f2e2ea8084de0847855d735d9ca212025-08-20T02:05:31ZengElsevierUrology Case Reports2214-44202024-11-015710285810.1016/j.eucr.2024.102858Adult nephroblastoma or Wilms' tumor: A rare entity - Case reportSalim Lachkar0Ahmed Ibrahimi1Imad Boualaoui2Hachem El Sayegh3Yassine Nouini4Corresponding author.; Department of Urology A, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Urology A, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Urology A, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Urology A, Ibn Sina University Hospital, Rabat, MoroccoDepartment of Urology A, Ibn Sina University Hospital, Rabat, MoroccoWilms' tumor (nephroblastoma) is rare in adults, comprising less than 5 % of renal cancers. This report details a 48-year-old male with persistent abdominal pain, weight loss, and fatigue, whose imaging showed a large, heterogeneous left renal mass with regional lymph node involvement. Post-nephrectomy histology confirmed nephroblastoma with a triphasic pattern. The patient underwent left radical nephrectomy and received adjuvant chemotherapy with doxorubicin, vincristine, and actinomycin D. Three months later, follow-up CT scans revealed no residual disease. This case underscores the diagnostic and therapeutic challenges of adult nephroblastoma and the need for more effective treatment protocols.http://www.sciencedirect.com/science/article/pii/S2214442024002122Adult nephroblastomaWilms' tumorRadical nephrectomyChemotherapy
spellingShingle Salim Lachkar
Ahmed Ibrahimi
Imad Boualaoui
Hachem El Sayegh
Yassine Nouini
Adult nephroblastoma or Wilms' tumor: A rare entity - Case report
Urology Case Reports
Adult nephroblastoma
Wilms' tumor
Radical nephrectomy
Chemotherapy
title Adult nephroblastoma or Wilms' tumor: A rare entity - Case report
title_full Adult nephroblastoma or Wilms' tumor: A rare entity - Case report
title_fullStr Adult nephroblastoma or Wilms' tumor: A rare entity - Case report
title_full_unstemmed Adult nephroblastoma or Wilms' tumor: A rare entity - Case report
title_short Adult nephroblastoma or Wilms' tumor: A rare entity - Case report
title_sort adult nephroblastoma or wilms tumor a rare entity case report
topic Adult nephroblastoma
Wilms' tumor
Radical nephrectomy
Chemotherapy
url http://www.sciencedirect.com/science/article/pii/S2214442024002122
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