Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke

Abstract Objectives This study investigated the effect of a comprehensive pulmonary rehabilitation (CPR) program on stroke-associated pneumonia (SAP) in patients with moderate-to-severe acute ischemic stroke (AIS) after thrombolysis. Methods This study was a prospective randomized controlled interve...

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Main Authors: QingSha Zhang, HongKun Liu, Jie Sun, HongGe Shi
Format: Article
Language:English
Published: BMC 2025-03-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02451-4
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author QingSha Zhang
HongKun Liu
Jie Sun
HongGe Shi
author_facet QingSha Zhang
HongKun Liu
Jie Sun
HongGe Shi
author_sort QingSha Zhang
collection DOAJ
description Abstract Objectives This study investigated the effect of a comprehensive pulmonary rehabilitation (CPR) program on stroke-associated pneumonia (SAP) in patients with moderate-to-severe acute ischemic stroke (AIS) after thrombolysis. Methods This study was a prospective randomized controlled intervention study. Eighty patients with moderate-to-severe AIS were divided into the conventional rehabilitation (CR) and CPR groups. Demographic and general clinical data were collected. Patients were evaluated by the Fatigue Severity Scale (FSS), Fugl–Meyer Assessment (FMA), and Fugl–Meyer balance (FMB). The incidence of pneumonia in the acute phase and the treatment efficacy were compared. Results FSS scores at T1 and T2 (2 weeks and 4 weeks after treatment), FMA scores, and FMB scores were higher than those at T0 (first day of admission). FSS scores in the CPR group were lower, while FMA and FMB scores were higher than those in the CR group at T1 and T2. The incidence of pneumonia was 10.00% in the CPR group and 25.00% in the CR group. The rehabilitation effective rate was 92.50% in the CPR group and 80.00% in the CR group, but the proportion of rehabilitation effect in the CPR group was higher than that in the CR group. Conclusions CPR program improves fatigue and motor function and reduces the occurrence of SAP in AIS patients.
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spelling doaj-art-9d8e03156cd144dbbed8d0632058e6512025-08-20T02:49:26ZengBMCEuropean Journal of Medical Research2047-783X2025-03-013011810.1186/s40001-025-02451-4Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic strokeQingSha Zhang0HongKun Liu1Jie Sun2HongGe Shi3Department of Rehabilitation Medicine, Zibo Central HospitalDepartment of Integrative Medicine and Orthopaedics, Zibo Central HospitalDepartment of Rehabilitation Medicine, Zibo Central HospitalDepartment of Rehabilitation Medicine, Zibo Central HospitalAbstract Objectives This study investigated the effect of a comprehensive pulmonary rehabilitation (CPR) program on stroke-associated pneumonia (SAP) in patients with moderate-to-severe acute ischemic stroke (AIS) after thrombolysis. Methods This study was a prospective randomized controlled intervention study. Eighty patients with moderate-to-severe AIS were divided into the conventional rehabilitation (CR) and CPR groups. Demographic and general clinical data were collected. Patients were evaluated by the Fatigue Severity Scale (FSS), Fugl–Meyer Assessment (FMA), and Fugl–Meyer balance (FMB). The incidence of pneumonia in the acute phase and the treatment efficacy were compared. Results FSS scores at T1 and T2 (2 weeks and 4 weeks after treatment), FMA scores, and FMB scores were higher than those at T0 (first day of admission). FSS scores in the CPR group were lower, while FMA and FMB scores were higher than those in the CR group at T1 and T2. The incidence of pneumonia was 10.00% in the CPR group and 25.00% in the CR group. The rehabilitation effective rate was 92.50% in the CPR group and 80.00% in the CR group, but the proportion of rehabilitation effect in the CPR group was higher than that in the CR group. Conclusions CPR program improves fatigue and motor function and reduces the occurrence of SAP in AIS patients.https://doi.org/10.1186/s40001-025-02451-4Comprehensive pulmonary rehabilitationAcute ischemic strokeFatigueMotor functionStroke-associated pneumonia
spellingShingle QingSha Zhang
HongKun Liu
Jie Sun
HongGe Shi
Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke
European Journal of Medical Research
Comprehensive pulmonary rehabilitation
Acute ischemic stroke
Fatigue
Motor function
Stroke-associated pneumonia
title Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke
title_full Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke
title_fullStr Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke
title_full_unstemmed Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke
title_short Reducing stroke-associated pneumonia through pulmonary rehabilitation in moderate-to-severe acute ischemic stroke
title_sort reducing stroke associated pneumonia through pulmonary rehabilitation in moderate to severe acute ischemic stroke
topic Comprehensive pulmonary rehabilitation
Acute ischemic stroke
Fatigue
Motor function
Stroke-associated pneumonia
url https://doi.org/10.1186/s40001-025-02451-4
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AT hongkunliu reducingstrokeassociatedpneumoniathroughpulmonaryrehabilitationinmoderatetosevereacuteischemicstroke
AT jiesun reducingstrokeassociatedpneumoniathroughpulmonaryrehabilitationinmoderatetosevereacuteischemicstroke
AT honggeshi reducingstrokeassociatedpneumoniathroughpulmonaryrehabilitationinmoderatetosevereacuteischemicstroke