Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil
Abstract This study explored a novel laccase production process utilizing perennial biomass and the aqueous phase from bio-oil. Experimental and techno-economic modeling were coupled to gain insight into and optimize the solid-state fermentation conditions for minimizing the laccase selling price. A...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-07-01
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| Series: | Bioresources and Bioprocessing |
| Online Access: | https://doi.org/10.1186/s40643-025-00924-2 |
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| _version_ | 1849238240788217856 |
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| author | Elmin Rahic Nicholas Cassady Kurt Rosentrater |
| author_facet | Elmin Rahic Nicholas Cassady Kurt Rosentrater |
| author_sort | Elmin Rahic |
| collection | DOAJ |
| description | Abstract This study explored a novel laccase production process utilizing perennial biomass and the aqueous phase from bio-oil. Experimental and techno-economic modeling were coupled to gain insight into and optimize the solid-state fermentation conditions for minimizing the laccase selling price. At relatively small scales, processing only 230 Mg of prairie biomass per year, a 5-year return on investment required a minimum laccase selling price of $0.05/kU, assuming a 10% discount rate. The associated sensitivity analysis showed the minimum laccase selling price to be most sensitive to parameters affecting laccase output from the plant, which included the number of batches produced per year and laccase recovery assumptions. Limitations and future outlooks were provided, emphasizing the need for further process optimization to minimize fermentation time and downstream losses. |
| format | Article |
| id | doaj-art-9d89c7007ffc4379929bad5a48085232 |
| institution | Kabale University |
| issn | 2197-4365 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Bioresources and Bioprocessing |
| spelling | doaj-art-9d89c7007ffc4379929bad5a480852322025-08-20T04:01:42ZengSpringerOpenBioresources and Bioprocessing2197-43652025-07-0112111310.1186/s40643-025-00924-2Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oilElmin Rahic0Nicholas Cassady1Kurt Rosentrater2Bioeconomy Institute, Iowa State UniversityDepartment of Biochemistry, Biophysics and Molecular Biology, Iowa State UniversityDepartment of Agricultural and Biosystems Engineering, Iowa State UniversityAbstract This study explored a novel laccase production process utilizing perennial biomass and the aqueous phase from bio-oil. Experimental and techno-economic modeling were coupled to gain insight into and optimize the solid-state fermentation conditions for minimizing the laccase selling price. At relatively small scales, processing only 230 Mg of prairie biomass per year, a 5-year return on investment required a minimum laccase selling price of $0.05/kU, assuming a 10% discount rate. The associated sensitivity analysis showed the minimum laccase selling price to be most sensitive to parameters affecting laccase output from the plant, which included the number of batches produced per year and laccase recovery assumptions. Limitations and future outlooks were provided, emphasizing the need for further process optimization to minimize fermentation time and downstream losses.https://doi.org/10.1186/s40643-025-00924-2 |
| spellingShingle | Elmin Rahic Nicholas Cassady Kurt Rosentrater Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil Bioresources and Bioprocessing |
| title | Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil |
| title_full | Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil |
| title_fullStr | Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil |
| title_full_unstemmed | Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil |
| title_short | Techno-economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio-oil |
| title_sort | techno economic analysis of a novel laccase production process utilizing perennial biomass and the aqueous phase of bio oil |
| url | https://doi.org/10.1186/s40643-025-00924-2 |
| work_keys_str_mv | AT elminrahic technoeconomicanalysisofanovellaccaseproductionprocessutilizingperennialbiomassandtheaqueousphaseofbiooil AT nicholascassady technoeconomicanalysisofanovellaccaseproductionprocessutilizingperennialbiomassandtheaqueousphaseofbiooil AT kurtrosentrater technoeconomicanalysisofanovellaccaseproductionprocessutilizingperennialbiomassandtheaqueousphaseofbiooil |