Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA.

Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA.

Besides the abundant ribosomal and transfer RNA transcripts (rRNA and tRNA, respectively), there are tens of thousands of long coding (mRNA) and non-coding transcripts (lncRNA) within each cell whose modification profiles have not yet been elucidated. One reason for this is that most mRNAs and lncRN...

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Bibliographic Details
Main Authors: Hagen Wesseling, Dennis Krug, Marvin Wehrheim, Michael W Göbel, Stefanie Kaiser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318697
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