Molecular mechanisms of polychlorinated biphenyls in breast cancer: insights from network toxicology and molecular docking approaches

Molecular mechanisms of polychlorinated biphenyls in breast cancer: insights from network toxicology and molecular docking approaches

BackgroundPolychlorinated biphenyls (PCBs) are environmental pollutants associated with various health issues, including breast cancer. This study investigates potential molecular mechanisms by which PCBs may influence breast cancer progression using computational and preliminary experimental approa...

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Bibliographic Details
Main Authors:	Xiaoyu Yang, Wenlong Liang, Zhenchu Feng, Guangyan Li, Xi Chen, Jianguo Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	polychlorinated biphenyls breast cancer immune cell infiltration TCGA molecular docking network toxicology
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1604993/full
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