Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study
Objective: To compare the short-term outcomes of metabolic surgery and intensive medical therapy in the management of diabetes mellitus among obese persons with type 2 diabetes mellitus. Methods: The quasi-experimental study was conducted at the Pakistan Institute of Medical Sciences, Islamabad,...
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Pakistan Medical Association
2025-01-01
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| Series: | Journal of the Pakistan Medical Association |
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| Online Access: | https://jpma.org.pk/index.php/public_html/article/view/10425 |
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| author | Zahra Raza Muhammad Burhan Ul Haq Tashfeen Imtiaz Muhammad Adnan Khokhar Aatif Inam |
| author_facet | Zahra Raza Muhammad Burhan Ul Haq Tashfeen Imtiaz Muhammad Adnan Khokhar Aatif Inam |
| author_sort | Zahra Raza |
| collection | DOAJ |
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Objective: To compare the short-term outcomes of metabolic surgery and intensive medical therapy in the management of diabetes mellitus among obese persons with type 2 diabetes mellitus.
Methods: The quasi-experimental study was conducted at the Pakistan Institute of Medical Sciences, Islamabad, Pakistan, from March 2018 to February 2019, and comprised obese type 2 diabetes mellitus patients of either gender aged 20-65 years. Those undergoing metabolic and bariatric surgery were assigned group A, while those undergoing intensive medical therapy formed control group B. All patients were followed up for 6 months to monitor their metabolic profile, including body mass index, glycosylated haemoglobin and fasting plasma glucose. Data was analysed using SPSS 20.
Results: Of the 72 patients, 36(50%) were in group A; 23(63.9%) females and 13(36.1%) males with mean age 41.2 years (SD± 10.2). The remaining 36(50%) patients were in group B; 22(61.1%) males and 14(38.9%) females with mean age 42.5 years (SD ± 10.6) (p>0.05). At 6 months, mean body mass index, glycosylated haemoglobin and fasting plasma glucose values were significantly lower in group A compared to group B (p<0.001). There were 33(91.7%) patients in group A with remission of diabetes compared to 1(2.8%) patient in group B (p<0.001).
Conclusion: Bariatric surgery was found to produce a good early outcome in the management of diabetes in the obese population, leading to remission post-surgery.
Key Words: Bariatric surgery, Metabolic surgery, Obese T2DM, Diabetes remission, Diabetes.
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| format | Article |
| id | doaj-art-9d745b8d973d417a87d89c88e3d9c86a |
| institution | DOAJ |
| issn | 0030-9982 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj-art-9d745b8d973d417a87d89c88e3d9c86a2025-08-20T02:41:24ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822025-01-01750210.47391/JPMA.10425Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental studyZahra Raza0Muhammad Burhan Ul Haq1Tashfeen Imtiaz2Muhammad Adnan Khokhar3Aatif Inam4Department of General Surgery, Pakistan Institute of Medical Sciences, Islamabad, PakistanDepartment of General Surgery, Pakistan Institute of Medical Sciences, Islamabad, PakistanDepartment of General Surgery, Pakistan Institute of Medical Sciences, Islamabad, PakistanDepartment of General Surgery, Pakistan Institute of Medical Sciences, Islamabad, PakistanDepartment of General Surgery, Pakistan Institute of Medical Sciences, Islamabad, Pakistan Objective: To compare the short-term outcomes of metabolic surgery and intensive medical therapy in the management of diabetes mellitus among obese persons with type 2 diabetes mellitus. Methods: The quasi-experimental study was conducted at the Pakistan Institute of Medical Sciences, Islamabad, Pakistan, from March 2018 to February 2019, and comprised obese type 2 diabetes mellitus patients of either gender aged 20-65 years. Those undergoing metabolic and bariatric surgery were assigned group A, while those undergoing intensive medical therapy formed control group B. All patients were followed up for 6 months to monitor their metabolic profile, including body mass index, glycosylated haemoglobin and fasting plasma glucose. Data was analysed using SPSS 20. Results: Of the 72 patients, 36(50%) were in group A; 23(63.9%) females and 13(36.1%) males with mean age 41.2 years (SD± 10.2). The remaining 36(50%) patients were in group B; 22(61.1%) males and 14(38.9%) females with mean age 42.5 years (SD ± 10.6) (p>0.05). At 6 months, mean body mass index, glycosylated haemoglobin and fasting plasma glucose values were significantly lower in group A compared to group B (p<0.001). There were 33(91.7%) patients in group A with remission of diabetes compared to 1(2.8%) patient in group B (p<0.001). Conclusion: Bariatric surgery was found to produce a good early outcome in the management of diabetes in the obese population, leading to remission post-surgery. Key Words: Bariatric surgery, Metabolic surgery, Obese T2DM, Diabetes remission, Diabetes. https://jpma.org.pk/index.php/public_html/article/view/10425Bariatric SurgeryMetabolic SurgeryObese T2DMDiabetes RemissionDiabetes |
| spellingShingle | Zahra Raza Muhammad Burhan Ul Haq Tashfeen Imtiaz Muhammad Adnan Khokhar Aatif Inam Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study Journal of the Pakistan Medical Association Bariatric Surgery Metabolic Surgery Obese T2DM Diabetes Remission Diabetes |
| title | Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study |
| title_full | Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study |
| title_fullStr | Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study |
| title_full_unstemmed | Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study |
| title_short | Short-term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics: a quasi-experimental study |
| title_sort | short term outcome of metabolic surgery versus intensive medical therapy among obese type 2 diabetics a quasi experimental study |
| topic | Bariatric Surgery Metabolic Surgery Obese T2DM Diabetes Remission Diabetes |
| url | https://jpma.org.pk/index.php/public_html/article/view/10425 |
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