Antioxidant and neuroprotective effects of nutriosomes and grape pomace phytochemicals in a cell model of oxidative stress and mouse model of Parkinson disease

Antioxidant and neuroprotective effects of nutriosomes and grape pomace phytochemicals in a cell model of oxidative stress and mouse model of Parkinson disease

Abstract The aim of the present study was to evaluate the effectiveness of a Cannonau pomace extract loaded in nutriosomes in intestinal oxidative stress and a subacute model of Parkinson disease and compare the results with those previously obtained with a Nasco pomace extract loaded in the same nu...

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Bibliographic Details
Main Authors: Mohamad Allaw, Matteo Perra, Pathik Parekh, Marcello Serra, Jacopo Marongiu, Ines Castangia, Federica Fulgheri, Pierluigi Caboni, Giulia Tolle, Francesco Corrias, Fabiano Asunis, Gabriele Giua, Firoznezhad Mohammad, Mansureh Ghavam, Micaela Morelli, Maria Manconi, Maria Letizia Manca
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Phospholipid vesicles
Neurodegeneration
Antioxidant activity
Neuroprotection
Nanotechnology
Caco-2 cells
Online Access:https://doi.org/10.1038/s41598-025-95060-4
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