Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men
The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/280724 |
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| _version_ | 1849399215749332992 |
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| author | Mario Amore Marco Innamorati Sara Costi Leo Sher Paolo Girardi Maurizio Pompili |
| author_facet | Mario Amore Marco Innamorati Sara Costi Leo Sher Paolo Girardi Maurizio Pompili |
| author_sort | Mario Amore |
| collection | DOAJ |
| description | The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T levels and depression is uncertain, many hypogonadal men suffer from depression and vice versa several depressed patients are affected by hypogonadism. Supplementation with testosterone failed to show sound evidence of effectiveness in the treatment of depression. Nevertheless, testosterone supplementation has proved to be effective on some domains significant for the quality of life of aged patients with PADAM (sexual function and cognitive functions, muscular strengths). |
| format | Article |
| id | doaj-art-9d71829dd1e54409bb8d9a6283a56d53 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-9d71829dd1e54409bb8d9a6283a56d532025-08-20T03:38:23ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/280724280724Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging MenMario Amore0Marco Innamorati1Sara Costi2Leo Sher3Paolo Girardi4Maurizio Pompili5Department of Neurosciences, Institute of Psychiatry, University of Parma, Piazza Matteotti 9, 43100 Parma, ItalyDepartment of Neurosciences, Institute of Psychiatry, University of Parma, Piazza Matteotti 9, 43100 Parma, ItalyDepartment of Neurosciences, Institute of Psychiatry, University of Parma, Piazza Matteotti 9, 43100 Parma, ItalyDepartment of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USADepartment of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, ItalyDepartment of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, ItalyThe aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T levels and depression is uncertain, many hypogonadal men suffer from depression and vice versa several depressed patients are affected by hypogonadism. Supplementation with testosterone failed to show sound evidence of effectiveness in the treatment of depression. Nevertheless, testosterone supplementation has proved to be effective on some domains significant for the quality of life of aged patients with PADAM (sexual function and cognitive functions, muscular strengths).http://dx.doi.org/10.1155/2012/280724 |
| spellingShingle | Mario Amore Marco Innamorati Sara Costi Leo Sher Paolo Girardi Maurizio Pompili Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men International Journal of Endocrinology |
| title | Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men |
| title_full | Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men |
| title_fullStr | Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men |
| title_full_unstemmed | Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men |
| title_short | Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men |
| title_sort | partial androgen deficiency depression and testosterone supplementation in aging men |
| url | http://dx.doi.org/10.1155/2012/280724 |
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