Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery

Abstract. Objective. To assess the role of a nurse-assisted early warning intervention in improving prophylaxis against obstetric venous thromboembolism (VTE) and preventing VTE following cesarean delivery (CD). Methods. A prospective cohort study conducted between January 1, 2020, and December 30,...

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Main Authors: Yang Pan, Jue Li, Bichao Wan, Dongying Fu, Shijiang Chen, Fuying Tao, Jianan Jiang, Yingying Tian
Format: Article
Language:English
Published: Wolters Kluwer Health 2024-10-01
Series:Maternal-Fetal Medicine
Online Access:http://journals.lww.com/10.1097/FM9.0000000000000245
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author Yang Pan
Jue Li
Bichao Wan
Dongying Fu
Shijiang Chen
Fuying Tao
Jianan Jiang
Yingying Tian
author_facet Yang Pan
Jue Li
Bichao Wan
Dongying Fu
Shijiang Chen
Fuying Tao
Jianan Jiang
Yingying Tian
author_sort Yang Pan
collection DOAJ
description Abstract. Objective. To assess the role of a nurse-assisted early warning intervention in improving prophylaxis against obstetric venous thromboembolism (VTE) and preventing VTE following cesarean delivery (CD). Methods. A prospective cohort study conducted between January 1, 2020, and December 30, 2022, enrolled pregnant women who underwent CD in the obstetric unit of Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital. The patients were assigned to a control group (routine nursing care) or the intervention group (nurse-assisted early warning intervention) depending on whether or not the nurse-assisted early warning intervention had been implemented. The χ2 test and Student’s t-test were used for statistical analysis. The primary outcome was the incidence of systemic VTE following CD, and secondary outcomes were the rates of mechanical or pharmacologic prophylaxis receipts for VTE and the frequency and severity of adverse events related to pharmacologic prophylaxis. Results. A total of 27,074 cases were enrolled. The incidence of symptomatic VTE following CD was significantly lower in the intervention group (0.29 per 1000 deliveries) than in the control group (2.4 per 1000 deliveries) (P < 0.001). Significantly more cases received mechanical and pharmacological VTE prophylaxis in the intervention group than in the control group (respectively, 19.8% vs. 12.6% receiving mechanical prophylaxis and 0.9% vs. 0.2% receiving pharmacological prophylaxis). No cases of life-threatening bleeding occurred in either group. Conclusion. The application of nurse-assisted early warning intervention may be an effective method for preventing VTE following CD.
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publishDate 2024-10-01
publisher Wolters Kluwer Health
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spelling doaj-art-9d712b6b16d14dbc8582ea6693df5b9d2025-08-20T03:12:22ZengWolters Kluwer HealthMaternal-Fetal Medicine2096-69542641-58952024-10-016422523110.1097/FM9.0000000000000245202410000-00004Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean DeliveryYang Pan0Jue Li1Bichao Wan2Dongying Fu3Shijiang Chen4Fuying Tao5Jianan Jiang6Yingying Tian7Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Department of Operating Room Nurses, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China.Abstract. Objective. To assess the role of a nurse-assisted early warning intervention in improving prophylaxis against obstetric venous thromboembolism (VTE) and preventing VTE following cesarean delivery (CD). Methods. A prospective cohort study conducted between January 1, 2020, and December 30, 2022, enrolled pregnant women who underwent CD in the obstetric unit of Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital. The patients were assigned to a control group (routine nursing care) or the intervention group (nurse-assisted early warning intervention) depending on whether or not the nurse-assisted early warning intervention had been implemented. The χ2 test and Student’s t-test were used for statistical analysis. The primary outcome was the incidence of systemic VTE following CD, and secondary outcomes were the rates of mechanical or pharmacologic prophylaxis receipts for VTE and the frequency and severity of adverse events related to pharmacologic prophylaxis. Results. A total of 27,074 cases were enrolled. The incidence of symptomatic VTE following CD was significantly lower in the intervention group (0.29 per 1000 deliveries) than in the control group (2.4 per 1000 deliveries) (P < 0.001). Significantly more cases received mechanical and pharmacological VTE prophylaxis in the intervention group than in the control group (respectively, 19.8% vs. 12.6% receiving mechanical prophylaxis and 0.9% vs. 0.2% receiving pharmacological prophylaxis). No cases of life-threatening bleeding occurred in either group. Conclusion. The application of nurse-assisted early warning intervention may be an effective method for preventing VTE following CD.http://journals.lww.com/10.1097/FM9.0000000000000245
spellingShingle Yang Pan
Jue Li
Bichao Wan
Dongying Fu
Shijiang Chen
Fuying Tao
Jianan Jiang
Yingying Tian
Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery
Maternal-Fetal Medicine
title Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery
title_full Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery
title_fullStr Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery
title_full_unstemmed Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery
title_short Effect of Nurse-Assisted Early Warning Intervention for Prevention of Venous Thromboembolism Following Cesarean Delivery
title_sort effect of nurse assisted early warning intervention for prevention of venous thromboembolism following cesarean delivery
url http://journals.lww.com/10.1097/FM9.0000000000000245
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